Antibiotic dosing study for patients on heart-lung support
Part of Heart & circulation, Infections clinical trials.
This study looks at how certain antibiotics behave in your body when you are on VA-ECMO. The goal is to find the right dose to treat your infection effectively and safely.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are on VA-ECMO, a machine that pumps and oxygenates your blood.
- You need to start a new antibiotic from a specific group: Piperacillin-Tazobactam, Cefepime, or Meropenem.
- You have not taken this antibiotic before going on ECMO.
- Doctors expect you to survive for at least another day.
- You are not pregnant or breastfeeding.
- You agree to participate, or your trusted person agrees.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how anti-infection drugs work in critically ill patients who are on ECMO, a machine that helps the heart and lungs. The goal is to find the right doses so the drugs work better and are safer for people in this condition.
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
This study will look at whether “left ventricular unloading” (using a device like IABP or Impella) helps people who are in cardiogenic shock while on VA ECMO. It compares outcomes for people who get unloading versus those who stay on VA ECMO alone.
This trial looks at using a specific heart-lung support machine (the EUROSETS ECMOLIFE system) for adults who need urgent “extra” circulation support. It may help clinicians understand how well the device works in serious situations like shock, cardiac arrest, or after heart surgery.
This trial studies whether using a life-support machine called ECMO (extra support for the heart and lungs) helps people who develop shock right after a heart attack. It aims to improve outcomes when blood flow is failing and organs may be struggling.
Hear when a new Cardiogenic Shock trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.