Clin2
NCT06343402Likely a fitRecruiting

Study of BBO-8520 for advanced KRAS G12C lung cancer

Non-small Cell Lung CancerMetastatic Non-Small Cell Lung CancerNSCLCKRAS G12CMetastatic Lung CancerAdvanced Lung Carcinoma

Treatments studied

Part of Cancer, Lungs & breathing clinical trials.

This trial tests a new oral medication called BBO-8520 for advanced lung cancer with a specific gene change (KRAS G12C mutation). It aims to see if the drug is safe and effective, and may be combined with another drug (pembrolizumab) in some groups.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
350 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have a type of lung cancer called non-small cell lung cancer that has a specific change called KRAS G12C mutation.
  • Your cancer is advanced (cannot be removed by surgery) or has spread to other parts of the body.
  • You have at least one tumor that can be seen on a scan.
  • You are generally able to do daily activities with little to no help (ECOG 0-1).
  • If you have had brain metastases, they must be treated and stable.
  • You must not have had another cancer in the last 2 years (except for certain types like skin cancer).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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