New drug combo vs standard therapy for KRAS G12C lung cancer
Part of Cancer, Lungs & breathing clinical trials.
This trial tests two new targeted drugs (IN10018 and D-1553) together as a first treatment for advanced non-squamous lung cancer with a specific KRAS G12C mutation. It compares this combination to standard therapy to see if it works better.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have advanced (stage IIIB/IV) non-squamous non-small cell lung cancer
- Your cancer has a specific KRAS G12C mutation confirmed by a central lab
- You are between 18 and 80 years old
- You have not had any prior treatment for advanced or metastatic lung cancer
- You are in good enough health to be up and about (ECOG 0-1) and have adequate organ function
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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