Clinical trials
GERD clinical trials
Below are recruiting gerd clinical trials, each written for real people, not researchers. We’re tracking 54 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07700342Recruiting
Could an evening gel improve sleep for nighttime reflux?
This trial tests a topical therapy you apply at night to see if it can improve sleep for people with non-erosive GERD who still have nighttime symptoms even while taking a morning acid reducer.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06617013Recruiting
GERD in children with cystic fibrosis
This study looks at GERD (reflux) in children with cystic fibrosis. It aims to understand how common it is and how it affects them, which could lead to better care.
Durham, North CarolinaAges 2–18 - NCT07678177Recruiting
Study of tegoprazan for patients with GERD
This study looks at how well and how safely the drug tegoprazan works for people with gastroesophageal reflux disease (GERD). It may help if you have symptoms like heartburn or acid reflux.
SeoulAges 19 years+ - NCT07634614Enrolling by invitation
Speech therapy for reflux-related bloating and belching
This trial tests whether speech and language therapy can help reduce bloating, belching, and other air-related symptoms in people with acid reflux (GERD). Researchers will measure how much the therapy improves these symptoms before and after treatment.
Schlieren, Canton of ZurichAges 18 years+ - NCT07544433Recruiting
Breathing Training to Help Reduce Acid Reflux
This study tests whether special diaphragm breathing exercises (using the muscle below your lungs that controls breathing) can reduce acid reflux symptoms. You'll learn and practice these exercises over time to see if they help your GERD without needing more medication.
Changhua, Changhua CountyAges 20–80 - NCT07437768Enrolling by invitation
Vonoprazan test for acid reflux that doesn't respond to standard medicine
This trial tests a medicine called vonoprazan for people whose acid reflux symptoms (like heartburn or coughing) don't get better with usual treatment. It aims to see if vonoprazan can help control those symptoms.
New Taipei City, TaiwanAges 20–75 - NCT06641375Recruiting
Heat treatment for chronic acid reflux (AREA study)
This trial tests a new way to treat GERD (chronic acid reflux) using a tiny camera and a device that delivers a gentle heat treatment (argon plasma coagulation) to the area where the stomach meets the esophagus. It's compared to a 'sham' procedure (you won't know which you get) to see if it stops acid from backing up better than medicine alone.
Hyderabad, TelanganaAges 18–70 - NCT06084572Recruiting
Study of pH-impedance tests for GERD diagnosis
This trial looks at how well a special test (pH-impedance) can diagnose GERD (acid reflux disease) when done correctly. It will use a new way to read the test results to see if it helps doctors classify GERD better.
AnderlechtAges 18–80 - NCT05870163Recruiting
Registry study of RefluxStop for GERD patients
This registry study follows people with long-term acid reflux (GERD) who get the RefluxStop treatment. It mainly collects real-world safety and performance information to see how well the device helps over time.
FriedrichshafenAges 18 years+ - NCT06114836Recruiting
Feeding therapy for GERD in infants born early
This study tests whether a special feeding method can help infants in the NICU who have been diagnosed with GERD (acid reflux) using a probe that measures acid and non-acid reflux. It aims to find a treatment that may reduce reflux symptoms without medication.
Columbus, OhioAges 1 day–8 months - NCT05066594Recruiting
Registry for a procedure to treat long-term reflux
This is an observational study (no experimental treatment) that follows people who choose a specific procedure called transoral incisionless fundoplication (TIF) with the EsophyX device for long-term acid reflux. It aims to track outcomes for up to 5 years at San Raffaele Hospital.
MilanAges 18–80 - NCT04945304Recruiting
9-Step magnetic revisional weight-loss surgery
This trial studies a specific 9-step approach using magnetic technology for people having revisional bariatric (weight-loss) surgery. It may help improve how safely and effectively surgery is done for people who qualify.
Maracaibo, ZuliaAges 18–65 - NCT07797959Recruiting
Thread acupuncture plus standard reflux treatment
This study tests whether adding thread-embedding acupuncture to standard acid-reducing medication helps people with gastroesophageal reflux disease (GERD) feel better. It may offer an extra option for managing symptoms like heartburn and regurgitation.
Ho Chi Minh CityAges 18–60 - NCT07707011Enrolling by invitation
Comparing two test-guided treatments for acid reflux
This trial compares two ways to choose the best treatment for people with frequent acid reflux. It tests whether using a simple test (called PCAB-guided) is as good as a more detailed test (called physiologic test-guided) for deciding on the right medicine. The goal is to find a more practical and effective approach.
Bangkok Noi, BangkokAges 18–70 - NCT07667894Recruiting
Online mindfulness for emotional distress in GERD
This study tests an online mindfulness program called MIED to see if it can help reduce emotional distress for people with GERD (chronic acid reflux). It involves weekly online sessions and questionnaires over several weeks.
Beijing, Beijing MunicipalityAges 18–65 - NCT06348420Recruiting
New procedure vs. acid-reducing pills for GERD
This study compares a new procedure called anti-reflux mucosal valvuloplasty (ARMV) to acid-reducing medicines (PPIs) for treating GERD. It may help people who have had reflux for a long time and need daily PPIs.
Jinan, ShandongAges 18–60 - NCT07624383Recruiting
New topical treatment for nonerosive acid reflux disease
This study tests a new topical treatment for people with chronic heartburn and acid regurgitation who don't have erosions (damage) in their esophagus. The treatment is applied directly to the affected area and may help relieve symptoms without taking daily pills.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06564246RecruitingPhase 4
Comparing Vonoprazan vs. Pantoprazole for GERD
This trial tests a newer medication called vonoprazan against the standard treatment pantoprazole for patients with gastroesophageal reflux disease (GERD). The goal is to see which one works better for controlling symptoms like heartburn and acid reflux over 8 weeks.
GizaAges 17–60 - NCT07556289RecruitingPhase 2
Minimally invasive reflux surgery for Asian patients with severe heartburn
This trial tests a newer, less invasive surgical procedure called TIF (Transoral Incisional Fundoplication) for patients with severe acid reflux and regurgitation that hasn't improved with high-dose medications. The procedure is done through the mouth rather than the abdomen, and researchers will follow patients for 5 years to see if it works and is safe in Asian populations.
Hong KongAges 18–80 - NCT07506746Recruiting
Study on esophagus movement
This study tracks patients with reflux, swallowing problems, or other esophageal symptoms to understand how the esophagus moves. It may help if you have heartburn, regurgitation, or related issues like cough or chest pain.
Milan, LombardyAges 18 years+ - NCT07421011RecruitingPhase 1
Comparing two forms of a drug for healthy volunteers
This study tests two different versions of a drug called Trimedat to see if they work the same way in the body. It is for healthy volunteers to understand how the drug is absorbed and if it is safe.
Saint PetersburgAges 18–45 - NCT06757296Recruiting
Endoscopic revision of sleeve gastrectomy for reflux or poor weight loss
This study tests a new, less invasive way to convert a sleeve gastrectomy into a different type of weight-loss surgery (SASI) in people who have ongoing gastroesophageal reflux or haven't lost enough weight. The goal is to see if this endoscopic procedure can improve reflux and help with weight loss without the need for a traditional surgery.
SingaporeAges 21–65 - NCT07268820RecruitingPhase 4
Nighttime heartburn treatment for erosive GERD
This trial tests a treatment for nighttime heartburn caused by GERD, a condition where stomach acid damages the esophagus. It is for adults who have had nighttime heartburn for more than 3 months and have been diagnosed with erosive GERD.
AnsanAges 19 years+
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GERD trials by city
Studies with a site in or near these metro areas.
GERD trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for gerd?
- Yes. Clin2 currently lists 54 recruiting gerd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gerd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gerd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.