Clinical trials
GERD clinical trials
Below are recruiting gerd clinical trials, each written for real people, not researchers. We’re tracking 56 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06617013Recruiting
GERD in children with cystic fibrosis
This study looks at GERD (reflux) in children with cystic fibrosis. It aims to understand how common it is and how it affects them, which could lead to better care.
Durham, North CarolinaAges 2–18 - NCT07700342Recruiting
Could an evening gel improve sleep for nighttime reflux?
This trial tests a topical therapy you apply at night to see if it can improve sleep for people with non-erosive GERD who still have nighttime symptoms even while taking a morning acid reducer.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT06613438Recruiting
New wearable device for GERD symptoms
This study tests a new wearable device (eGERD) that aims to reduce symptoms of GERD (heartburn and regurgitation). The trial will check if the device is safe and works well without needing medication.
Chicago, IllinoisAges 22–75 - NCT06114836Recruiting
Feeding therapy for GERD in infants born early
This study tests whether a special feeding method can help infants in the NICU who have been diagnosed with GERD (acid reflux) using a probe that measures acid and non-acid reflux. It aims to find a treatment that may reduce reflux symptoms without medication.
Columbus, OhioAges 1 day–8 months - NCT05870163Recruiting
Registry study of RefluxStop for GERD patients
This registry study follows people with long-term acid reflux (GERD) who get the RefluxStop treatment. It mainly collects real-world safety and performance information to see how well the device helps over time.
FriedrichshafenAges 18 years+ - NCT06084572Recruiting
Study of pH-impedance tests for GERD diagnosis
This trial looks at how well a special test (pH-impedance) can diagnose GERD (acid reflux disease) when done correctly. It will use a new way to read the test results to see if it helps doctors classify GERD better.
AnderlechtAges 18–80 - NCT06457334Recruiting
Getting rid of H. pylori for GERD relief
This study tests whether getting rid of H. pylori bacteria in the stomach can help improve symptoms of GERD (acid reflux). It is for people who have been diagnosed with GERD through an endoscopy and also have H. pylori.
AsyutAges Any age - NCT06641375Recruiting
Heat treatment for chronic acid reflux (AREA study)
This trial tests a new way to treat GERD (chronic acid reflux) using a tiny camera and a device that delivers a gentle heat treatment (argon plasma coagulation) to the area where the stomach meets the esophagus. It's compared to a 'sham' procedure (you won't know which you get) to see if it stops acid from backing up better than medicine alone.
Hyderabad, TelanganaAges 18–70 - NCT07678177Recruiting
Study of tegoprazan for patients with GERD
This study looks at how well and how safely the drug tegoprazan works for people with gastroesophageal reflux disease (GERD). It may help if you have symptoms like heartburn or acid reflux.
SeoulAges 19 years+ - NCT07544433Recruiting
Breathing Training to Help Reduce Acid Reflux
This study tests whether special diaphragm breathing exercises (using the muscle below your lungs that controls breathing) can reduce acid reflux symptoms. You'll learn and practice these exercises over time to see if they help your GERD without needing more medication.
Changhua, Changhua CountyAges 20–80 - NCT07634614Enrolling by invitation
Speech therapy for reflux-related bloating and belching
This trial tests whether speech and language therapy can help reduce bloating, belching, and other air-related symptoms in people with acid reflux (GERD). Researchers will measure how much the therapy improves these symptoms before and after treatment.
Schlieren, Canton of ZurichAges 18 years+ - NCT07437768Enrolling by invitation
Vonoprazan test for acid reflux that doesn't respond to standard medicine
This trial tests a medicine called vonoprazan for people whose acid reflux symptoms (like heartburn or coughing) don't get better with usual treatment. It aims to see if vonoprazan can help control those symptoms.
New Taipei City, TaiwanAges 20–75 - NCT06984484Recruiting
Afluxin for GERD: safety and performance study
This trial tests a new treatment called Afluxin for people with gastroesophageal reflux disease (GERD), which causes heartburn and regurgitation. It aims to see if Afluxin is safe and works better than a placebo (inactive control) to relieve symptoms.
GenovaAges 18–75 - NCT07063576RecruitingPhase 2/Phase 3
Baclofen for persistent heartburn or regurgitation
This trial tests whether the drug baclofen can help patients who still have acid reflux symptoms (heartburn or regurgitation) despite taking standard treatments like PPIs for 8 weeks. If you've tried PPIs and still have symptoms, this may be an option.
DhakaAges 18 years+ - NCT07227506Recruiting
Mucosal impedance testing for chronic esophagus issues
This trial uses a special device during an upper endoscopy to measure the electrical properties of the esophagus lining, which may help diagnose chronic reflux or swallowing problems.
Milwaukee, WisconsinAges 18 years+ - NCT07707011Enrolling by invitation
Comparing two test-guided treatments for acid reflux
This trial compares two ways to choose the best treatment for people with frequent acid reflux. It tests whether using a simple test (called PCAB-guided) is as good as a more detailed test (called physiologic test-guided) for deciding on the right medicine. The goal is to find a more practical and effective approach.
Bangkok Noi, BangkokAges 18–70 - NCT03886961Recruiting
Reflux band device trial for lung transplant recipients
This trial tests whether a Reflux Band™ placed around the upper swallowing tube area can reduce reflux (stomach acid coming up) in people who have had a lung transplant. If reflux is causing discomfort or lung irritation, reducing it may help you stay stable after transplant.
Gainesville, FloridaAges 18–80 - NCT06783751Recruiting
New surgical method to reduce acid reflux after weight loss surgery
This trial tests a modified version of sleeve gastrectomy that aims to reduce the risk of acid reflux (GERD) after surgery. It is for people aged 18–65 with a BMI between 35 and 55 who already have some degree of GERD and are planning to have weight loss surgery.
Orange, CaliforniaAges 18–65 - NCT04255693Recruiting
Real-life reflux study of diet and behavior changes
This study looks at how following specific diet and behavior changes affects symptoms of acid reflux (heartburn/regurgitation) in everyday life. It may help you understand what lifestyle steps improve reflux and how symptoms change over time.
MoscowAges 18–80 - NCT04422405Recruiting
One-anastomosis stomach bypass study for reflux and stomach changes
This study looks at how a one-anastomosis gastric bypass changes how your stomach and esophagus work, especially relating to acid reflux. You may be offered the planned surgery if you fit the weight and heartburn/reflux-related conditions, and the team will measure changes before and after.
Schlieren, Canton of ZurichAges 18–65 - NCT04506593Recruiting
GI Motility diagnosis registry for people with digestion movement problems
This trial is a registry, meaning it collects information about people being evaluated for problems with how the gut moves. It may help doctors better diagnose gastrointestinal motility disorders in the future.
Indianapolis, IndianaAges Any age - NCT04699591Recruiting
Domperidone for severe stomach movement problems
This trial looks at whether domperidone can help people ages 12–21 with symptoms from stomach not moving well when usual treatments haven’t worked. It’s designed for cases where other causes have been ruled out and patients are monitored for possible heart and hormone side effects.
Kansas City, MissouriAges 12–21 - NCT04901429Recruiting
Check truncal nerve procedure during weight-loss surgery
This study looks at a nerve-related surgical step (“truncal vagotomy”) during revision weight-loss surgery that changes a sleeve stomach to a gastric bypass. It may help improve outcomes for people who need this type of second surgery.
Dallas, TexasAges 18 years+ - NCT04945304Recruiting
9-Step magnetic revisional weight-loss surgery
This trial studies a specific 9-step approach using magnetic technology for people having revisional bariatric (weight-loss) surgery. It may help improve how safely and effectively surgery is done for people who qualify.
Maracaibo, ZuliaAges 18–65
Hear when a new GERD trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
GERD trials by city
Studies with a site in or near these metro areas.
GERD trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for gerd?
- Yes. Clin2 currently lists 56 recruiting gerd studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a gerd trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a gerd trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.