Chemoembolization before liver transplant for liver cancer
Part of Cancer, Digestive system clinical trials.
This trial tests whether using chemotherapy beads delivered directly to the liver (DEB-TACE) before a living donor liver transplant improves outcomes for people with liver cancer. If you have a tumor in the right side of the liver that fits certain size and number limits, and you are already scheduled for a transplant, this study may be an option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have viral hepatitis or cirrhosis and a diagnosis of liver cancer based on standard imaging or biopsy.
- Your liver function is good enough (Child-Pugh score A or B).
- Your tumor(s) are in the right side of the liver, and the total size plus number of tumors is 7 or less.
- You are able to care for yourself (ECOG score 0 or 1).
- You are scheduled to receive a liver transplant from a living donor.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new heat-sensitive embolic agent used during TACE (a procedure that blocks blood flow to tumors and delivers chemotherapy directly to the liver) for primary liver cancer. It aims to see if the agent is safe and effective for patients who need TACE treatment.
This trial tests giving chemotherapy directly into the liver artery (HAIC) combined with immunotherapy before surgery for liver cancer that can be removed but is too large or numerous for standard treatment. The goal is to shrink the tumor and improve surgery results.
This trial compares two types of tiny beads used in a liver cancer treatment called TACE to see which works better. If you have liver cancer that needs TACE and your liver is still working fairly well, you may be able to join.
This trial tests whether giving chemotherapy directly into the liver blood supply before a liver transplant can help people with liver cancer that is beyond standard transplant criteria. It may help lower cancer risk around the time of transplant while keeping people healthy enough to receive the transplant.
This trial is collecting information on how well a treatment (likely TACE, a procedure to block the tumor's blood supply) works for people with liver cancer that cannot be removed by surgery. It aims to see how safe and effective it is for patients who haven't had treatment before or who have a first recurrence.
This trial tests a combination of two treatments for advanced liver cancer that cannot be removed by surgery: drug-coated bead chemoembolization (DEB-TACE) and a chemotherapy infusion into the liver artery (SALOX-HAIC). The goal is to see if this combination can help shrink tumors and improve outcomes.
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