Radiation or ablation for ventricular tachycardia in heart disease
Part of Heart & circulation clinical trials.
This trial compares two treatments—radiation therapy or catheter ablation—for people with structural heart disease who have a type of fast heart rhythm called ventricular tachycardia. It aims to see which approach works better to prevent repeat episodes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have structural heart disease (like weak heart muscle, thickened walls, or scar tissue from a heart attack or other cause).
- You have had at least one episode of ventricular tachycardia (a fast heart rhythm from the lower chambers) that lasted more than 30 seconds or required a shock from an ICD.
- Your doctor has assessed your risk using a special score showing you are at moderate to high risk of having another VT episode or death.
- You are 18 years or older and expected to live longer than 3 months.
- You cannot be pregnant or breastfeeding.
- You have no other heart rhythm conditions like long QT syndrome or Brugada syndrome, and no reasons that make radiation or ablation unsafe for you.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial studies a radiation approach (called stereotactic body radiation therapy, or SBRT) to treat ventricular tachycardia (a dangerous heart rhythm) that keeps coming back. It aims to reduce the rhythm episodes in people who have already tried catheter ablation (a procedure to cauterize rhythm sources) or cannot have it.
This trial tests a focused type of radiation to treat ventricular tachycardia (VT) that keeps coming back despite other treatments. It may help people who cannot (or do not want to) have the usual catheter procedure to fix the rhythm.
This trial tests whether a single session of targeted radiation (radioablation) is as effective as three sessions for treating a dangerous heart rhythm called ventricular tachycardia in people with heart muscle disease. It's for those who continue to have episodes despite medication and catheter ablation.
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