Clin2
NCT06373042Possibly a fitNot yet recruiting

Tirofiban after successful clot removal for stroke

Stroke, Acute Ischemic

Part of Brain & nervous system, Heart & circulation clinical trials.

This trial tests a medication called tirofiban, which helps prevent blood clots, given after a successful procedure to remove a clot from a large brain artery. The goal is to see if it can reduce disability after a stroke when given within 24 hours of symptom onset.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
712 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be 18 years or older.
  • You must have had an acute ischemic stroke (a stroke caused by a blood clot) within the last 24 hours.
  • Your stroke must be severe enough (NIHSS score between 6 and 29).
  • Imaging scans (like CT or MRI) must show a blockage in a large brain artery.
  • You must have already had a procedure to remove the clot (thrombectomy) that successfully restored blood flow.
  • You cannot have certain bleeding risks, kidney problems, or be on blood thinners.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06987305Recruiting· Phase 3
Clot-busting medication before clot removal for late-arriving stroke

This trial tests whether adding a clot-busting medication (rhTNK-tPA) before a clot-removal procedure (thrombectomy) can improve outcomes for people who have a moderate-to-severe stroke and arrive at the hospital 4.5 to 24 hours after symptoms start. It's for those with a large artery blockage but still enough brain tissue that can be saved.

Wuhan, Hubei
NCT06768138Recruiting· Phase 3
Giving clot-busting medicine directly into the brain after successful blood flow restoration

This trial tests whether a clot-busting drug given directly into the brain artery can improve recovery after a major stroke caused by a blockage in the front part of the brain. The study is for people whose blood flow has already been successfully restored with standard treatments.

Nancy
NCT07537933Not yet recruiting· Phase 3
Tirofiban after successful clot removal for stroke

This trial tests whether giving a medication called tirofiban directly into the artery (intra-arterially) after a successful clot removal can improve recovery after a stroke. Tirofiban helps prevent new clots from forming, which may reduce the chance of another stroke.

Jinan, Shandong
NCT07111806Not yet recruiting· Phase 3
Tirofiban after delayed clot-busting treatment for stroke

This trial tests a medication called tirofiban given intravenously after standard thrombolysis to see if it improves recovery in people with acute ischemic stroke. It is for those whose symptoms have not improved or are getting worse after initial treatment.

Guangzhou, Guangdong
NCT06045156Recruiting
Tirofiban after clot-busting for stroke

This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.

Changchun, Jilin
NCT07135089Recruiting· Phase 3
Tirofiban before clot removal for large artery stroke

This trial tests whether adding a clot-preventing medication called tirofiban before a mechanical clot removal procedure can improve recovery in people with a certain type of stroke. It's for those with a large artery blockage in the front part of the brain who are able to start the procedure within 12 hours.

Shenyang, Liaoning

Hear when a new Stroke, Acute Ischemic trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.