Clot-busting medication before clot removal for late-arriving stroke
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether adding a clot-busting medication (rhTNK-tPA) before a clot-removal procedure (thrombectomy) can improve outcomes for people who have a moderate-to-severe stroke and arrive at the hospital 4.5 to 24 hours after symptoms start. It's for those with a large artery blockage but still enough brain tissue that can be saved.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You had a stroke that started between 4.5 and 24 hours ago.
- You had little or no disability before the stroke (for example, able to walk and care for yourself).
- Your stroke symptoms are at least moderate (NIHSS score of 5 or more).
- A brain scan shows a blockage in a major artery, and there is still salvageable brain tissue (as measured by special imaging).
- You are planning to have a procedure to remove the clot (endovascular thrombectomy).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests a clot-dissolving medication called rhTNK-tPA for people who had a stroke 4.5 to 24 hours ago. It aims to help those with certain types of blockages in the brain who are still having moderate to severe symptoms.
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