Blood Thinner Injection During Stroke Clot Removal
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests whether injecting a blood thinner called tirofiban directly into brain blood vessels during a stroke procedure helps prevent clots from forming again. If you've had a stroke caused by a large clot in your brain that was successfully removed, this study may help protect your recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Age 18 or older
- Stroke symptoms started within the last 24 hours and you underwent a clot removal procedure
- Brain imaging showed a large clot in your neck or brain arteries (carotid, middle cerebral artery)
- The clot was successfully removed during your procedure with no remaining narrowing
- Your brain damage score (ASPECTS) is 6 or higher on CT or MRI
- You were independent before your stroke (able to do daily activities)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests adding the anti-clotting drug tirofiban to standard clot removal for people who have a stroke due to a narrowed artery in the brain. The goal is to see if this combination improves outcomes without raising bleeding risk.
This trial tests whether giving tirofiban (a blood thinner) shortly after the standard clot-busting drug tenecteplase can improve recovery from a moderate stroke. It is for people who have had a stroke within the last few hours and do not have certain risk factors like irregular heart rhythm or recent bleeding.
This trial tests if a medication called tirofiban can help people who had a stroke 4.5 to 24 hours ago and received clot-dissolving treatment (IVT). If you have had a stroke and your symptoms did not improve or got worse after IVT, this study might offer a way to prevent further disability.
This trial tests whether giving a clot-dissolving medication directly into the brain's blood vessels during a standard procedure (mechanical thrombectomy) can improve outcomes for people with a stroke caused by a blockage in a medium-sized artery. It may be an option for patients who arrive at the hospital within 24 hours of symptom onset and have enough salvageable brain tissue.
This trial tests whether adding a second medicine (tirofiban) to standard clot-busting treatment can help people who are not improving after the first hour. It is for people with a moderate to severe stroke who are not candidates for a clot-removal procedure.
This trial tests whether a clot-busting medication given through a vein (intravenous thrombolysis) can safely treat acute ischemic stroke within 24 hours in people who have taken a newer oral blood thinner (NOAC) within the last 4 to 48 hours.
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