Clin2
NCT06387342Likely a fitRecruiting

Namodenoson for advanced pancreatic cancer

Pancreatic AdenocarcinomaPancreatic Cancer

Treatments studied

Part of Cancer, Digestive system, Hormones & metabolism clinical trials.

This trial tests an oral drug called Namodenoson for people with advanced pancreatic cancer that has not responded to previous treatments. The goal is to see if the drug can help slow the cancer's growth or improve symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
20 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have advanced pancreatic cancer that has spread or is not responding to treatment.
  • You have tried at least one prior cancer treatment, or you choose not to take standard therapy.
  • You are 18 years or older and have a performance status of 0 to 2 (able to care for yourself and up and about more than half the day).
  • Your blood counts and organ function (kidneys, liver, bone marrow) are within the ranges required by the study.
  • You are not pregnant, breastfeeding, and if applicable, you agree to use two effective birth control methods during the study and for one month after.
  • You do not have a serious heart condition, active uncontrolled infection, another cancer needing treatment, or other major medical issues that would make the study unsafe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07126158Recruiting· Phase 2
Radiation plus targeted drugs for advanced pancreatic cancer

This trial tests a combination of targeted radiation and two oral drugs (defactinib and avutometinib) for people with advanced pancreatic cancer that hasn't spread to distant organs. It may be an option if you've already had at least 2 months of chemo and your cancer is still locally advanced or borderline resectable.

St Louis, Missouri
NCT07756281Not yet recruiting· Phase 1
Study of SNV1521 with a RAS inhibitor for advanced pancreatic cancer

This trial tests a new combination treatment for pancreatic cancer that has spread or cannot be removed with surgery. The goal is to see if the combination can help control the cancer and is safe.

NCT06405490Recruiting· Phase 2
Chemo plus immunotherapy for first-line advanced pancreatic cancer

This trial tests a combination of chemotherapy (NALIRI-XELOX) plus a newer immunotherapy drug (AK104) as a first treatment for people with advanced pancreatic cancer that hasn't been treated yet. The goal is to see if this combination works better than standard treatments.

Beijing, Beijing Municipality
NCT06892054Recruiting· Phase 1
Targeted therapy plus chemo for advanced pancreatic cancer

This study tests a new targeted drug called sotorasib combined with standard chemotherapy for people with advanced pancreatic cancer that has a specific KRAS G12C mutation. The goal is to see if the combination works better than chemotherapy alone.

Avignon, France
NCT07736612Not yet recruiting· Phase 1/Phase 2
A new targeted drug for advanced pancreatic cancer

This trial tests a new drug that targets a common gene change (RAS) in advanced pancreatic cancer. It combines that drug with other treatments to see if it helps people whose cancer has not responded to or come back after prior therapy.

Hangzhou, Zhejiang
NCT07656376Not yet recruiting· Phase 2/Phase 3
New drug with chemo for advanced pancreatic cancer with KRAS G12D mutation

This trial tests a new drug (DN022150) combined with standard chemotherapy (AG) as a first treatment for advanced or metastatic pancreatic cancer that has a specific gene change called KRAS G12D. It may help people who haven't had other treatments for this stage of cancer.

Hear when a new Pancreatic Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.