Clin2
NCT06393543Possibly a fitNot yet recruiting

Tracking isolated STIC to prevent future cancer

BRCA MutationSerous Tubal Intraepithelial CarcinomaOvarian CarcinomaPeritoneal Carcinoma

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study tracks women who had a precancerous change in their fallopian tubes (called STIC) removed during surgery. It aims to learn how often this leads to a future cancer in the lining of the abdomen, so doctors can better monitor and prevent it.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
600 people
Ages
18 years to 100 years
Study type
Observational

Who can take part

  • You are a woman.
  • You had both fallopian tubes removed (with or without removal of the ovaries).
  • A biopsy of the removed tissue showed a precancerous change called STIC.
  • No invasive cancer was found at the time of your surgery or in the lab tests.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07764744Not yet recruiting
Blood test for early ovarian cancer detection in BRCA carriers

This study is testing a blood test that may help find ovarian cancer earlier in people with BRCA1 or BRCA2 gene changes. It involves giving blood samples before and after surgery to remove the ovaries and fallopian tubes, or over several years if you've had a precancerous lesion found.

New York, New York
NCT03296826Recruiting
Study for women with BRCA gene changes

This study follows women who carry BRCA1 or BRCA2 gene variants (or a gene variant of unclear meaning) to learn about their risks over time. It may help improve how genetic information is used to guide future care.

Okayama
NCT04251052Recruiting
Compare two surgeries to lower ovarian cancer risk in BRCA1 carriers

This study compares two risk-reducing surgery plans for people with a BRCA1 genetic change to see which approach helps lower ovarian cancer risk. You may be asked to have the study procedure sooner or later depending on your chosen plan.

Birmingham, Alabama
NCT06726330Not yet recruiting
Risk-reducing choices for women with gene changes

This study looks at different ways to lower the risk of ovarian and pelvic cancer in women who have certain gene changes. It may involve removing the fallopian tubes (fimbriectomy) as a preventive step, and compares different strategies to see which works best.

Lyon, France
NCT06312124Recruiting
Fallopian tube removal to prevent ovarian cancer

This study looks at removing fallopian tubes during other planned surgeries to help prevent ovarian cancer. You may be able to join if you are at least 45 years old, are female or assigned female at birth, and are having non-gynecologic surgery (like gallbladder or hernia repair).

Baltimore, Maryland
NCT07736300Not yet recruiting
Gene activity study in BRCA carriers with and without early cell changes

This study looks at gene activity in stored ovarian and fallopian tube tissue from people with and without BRCA gene mutations, to find early markers that might help prevent ovarian cancer. If you have a BRCA mutation, they are especially interested in a very early change called STIC, which can be a sign of future cancer risk.

Hear when a new BRCA Mutation trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.