Risk-reducing choices for women with gene changes
Part of Cancer, Women’s health & pregnancy clinical trials.
This study looks at different ways to lower the risk of ovarian and pelvic cancer in women who have certain gene changes. It may involve removing the fallopian tubes (fimbriectomy) as a preventive step, and compares different strategies to see which works best.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 35 and 50 years old.
- You have a gene change (mutation) in BRCA1, BRCA2, RAD51C, RAD51D, or PALB2 that increases your risk of ovarian or pelvic cancer.
- You are seeing a genetic counselor or doctor for cancer risk counseling.
- You have not had both ovaries or both fallopian tubes removed before.
- You have never had ovarian, fallopian tube, or primary peritoneal cancer.
- You have not gone through menopause yet.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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