Compare two surgeries to lower ovarian cancer risk in BRCA1 carriers
Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study compares two risk-reducing surgery plans for people with a BRCA1 genetic change to see which approach helps lower ovarian cancer risk. You may be asked to have the study procedure sooner or later depending on your chosen plan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are age 35 to 50 (inclusive).
- You are planning a risk-reducing surgery for BRCA1 (either remove ovaries and tubes, or remove tubes now and delay ovary removal).
- You have a confirmed BRCA1 mutation from a lab test, documented for this study.
- You have had recent pelvic imaging (ultrasound or MRI) and a blood CA-125 test within the last 180 days.
- You must be medically able to undergo the planned surgery and give informed consent.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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