Clin2
NCT06403735Possibly a fitRecruiting

Study of QLC1101 for advanced solid tumors with KRAS G12D mutation

Non-small Cell Lung CancerColorectal CancerPancreatic CancerSolid Tumor

Part of Cancer, Digestive system, Hormones & metabolism, Lungs & breathing clinical trials.

This trial tests a new drug, QLC1101, for people with advanced solid tumors that have a specific genetic change called KRAS G12D. It may be an option if you have tried other treatments or cannot take them.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1
Enrollment
250 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must have an advanced solid tumor that cannot be removed by surgery or has spread, and it must have the KRAS G12D mutation.
  • You must have tried standard treatment and it didn't work or you can't have it, or you choose not to.
  • You must be able to swallow pills and not have any major stomach or bowel problems that affect how the drug is absorbed.
  • You must have at least one tumor that can be measured on a CT or MRI scan.
  • You must be in fairly good health, able to do most daily activities (ECOG score 0 or 1), and expected to live at least 3 months.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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