Clin2
NCT06406790Possibly a fitRecruiting

Studying a new sealant for brain surgery

Leak, Cerebrospinal Fluid

Part of Brain & nervous system, Injuries & trauma clinical trials.

This trial tests a product called CraniSeal, which is used to help seal the covering of the brain (the dura) after surgery. It may lower the risk of fluid leaks after certain types of planned brain surgeries.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
224 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older.
  • You are scheduled for a planned (not emergency) brain surgery that requires opening the covering of the brain (the dura).
  • Your surgery is considered a clean procedure (no infection expected).
  • You agree to follow the study's schedule and procedures.
  • You are not pregnant or breastfeeding.
  • You do not have an active infection or a weakened immune system.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04498026Enrolling by invitation
Sealant tested to help close a spinal fluid leak opening

This study tests a glue-like dural sealant (Adherus™) to help seal and protect the covering around the spinal cord after a planned opening. It may help prevent or reduce problems related to spinal fluid leaking after certain elective spinal surgeries.

Duarte, California
NCT07651826Recruiting
Study of Immiseal Dural Sealant in Brain and Spine Surgery

This study tracks how well Immiseal, a special sealing material, works when applied during brain or spine surgery to prevent fluid leaks from the protective membrane around the brain and spinal cord. You'll be followed after surgery to see how well the sealant performs and if you have any side effects.

Riga
NCT07216157Recruiting
Sealant vs no sealant for skull base surgery

This trial tests whether using a sealant after skull base surgery helps prevent spinal fluid leaks. It compares patients who get a sealant with those who don't.

Warsaw
NCT07765862Not yet recruiting
Sealant for brain and spine surgery

This trial tests a new sealant called ArtiFix to close the protective layer around the brain and spinal cord during surgery. It may help prevent fluid leaks and help you recover.

NCT07092267Not yet recruiting
Sealant patch for brain or spine surgery

This trial tests a special patch called ArtiFix® that helps seal the protective membrane around the brain or spinal cord after surgery. It is designed for people who need an extra seal during their planned neurosurgery to prevent fluid leaks.

NCT05880680Recruiting
SEAL device registry for certain brain aneurysms treated through blood vessels

This study follows people who have a brain aneurysm that can be treated using the SEAL device placed from inside a blood vessel. It aims to track how well the treatment works and how safely it can be used in real-world care.

Itagüi, Medellín

Hear when a new Leak, Cerebrospinal Fluid trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.