Steroid treatment for radiation-induced bowel injury
Treatments studied
Part of Digestive system clinical trials.
This trial tests if local steroids can help heal bowel damage caused by radiation therapy for cancer. It may reduce pain, bleeding, and urgency, and improve quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had radiation therapy for cancer and developed moderate to severe bowel injury (grade II-III).
- You are at least 18 years old.
- Your doctor expects you to live for more than 1 year.
- You have not used steroid medications in the last 3 months.
- You do not have active infections, severe ulcers, or uncontrolled diabetes or high blood pressure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at how radiation therapy affects the intestines and may help find ways to predict and manage side effects. By participating, you could help doctors better understand and treat radiation-related gut problems.
This study tests whether giving a steroid medication (dexamethasone) as an enema can help reduce the side effect of radiation treatment on the rectal area. If you are getting radiation for rectal cancer and are bothered by rectal irritation, this might be a helpful addition to your care.
This trial tests whether a special dietary supplement can help protect the rectum from radiation damage during chemoradiation for locally advanced rectal cancer. If it works, it may reduce painful bowel symptoms like frequent stools and cramping.
This trial tests a dietary supplement to help heal damage inside the rectum caused by pelvic radiation therapy. If you have mild to moderate rectal bleeding but no signs of cancer recurrence, you may be able to join.
This trial tests whether combining thalidomide and glutamine helps people with bleeding caused by past radiation treatment to the abdomen or pelvis. The medication may reduce inflammation and help healing.
This study looks at how a hormone called GLP-2 (which helps protect the gut) changes during radiation therapy to the belly or pelvis, and whether it relates to side effects like radiation enteritis (inflammation of the gut). The goal is to better understand and possibly predict these side effects to improve care.
Hear when a new Radiation-Induced Intestinal Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.