Clin2
NCT06421948Possibly a fitRecruiting

Linperlisib and chidamide for PTCL

Peripheral T-cell Lymphoma

Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.

This trial tests two pills—linperlisib and chidamide—for people with a type of lymphoma called PTCL. The combination might work better together than either alone.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
134 people
Ages
18 years to 80 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old (or up to 80 for some parts of the study).
  • You have been newly diagnosed with a type of PTCL, except for certain subtypes like anaplastic large cell, NK/T-cell, or skin lymphoma.
  • You are generally well enough to do daily activities (ECOG score 0-2).
  • Your blood counts (hemoglobin, platelets, and neutrophils) are within safe levels.
  • Your liver and kidney function tests are within acceptable limits.
  • You have not had a PI3K inhibitor before (a type of targeted therapy).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06712173Not yet recruiting· Phase 1
Combination of two targeted drugs for relapsed or refractory PTCL

This trial tests a new combination of two pills—linperlisib and an EZH2 inhibitor—for people with a type of lymphoma called peripheral T-cell lymphoma (PTCL) that has come back or not responded to previous treatment. The goal is to see if this combination can help control the disease with manageable side effects.

NCT06548347Not yet recruiting· Phase 2/Phase 3
Adding linperlisib to chemo for newly diagnosed peripheral T-cell lymphoma

This study tests whether adding a targeted drug called linperlisib to the standard chemo regimen (CHOP) is better than CHOP alone for people with newly diagnosed peripheral T-cell lymphoma. It may help shrink tumors and control the lymphoma for longer.

NCT06151106Recruiting· Phase 2
Study of Chidamide and Duvalisib for Relapsed or Resistant T-Cell Lymphoma

This trial tests a combination of two targeted drugs, Chidamide and Duvalisib, for people with peripheral T-cell lymphoma or NK/T-cell lymphoma that has come back or not responded to previous treatment. The goal is to see if this drug combination can help shrink or control the lymphoma.

Xiamen, Fujian
NCT04512534Recruiting· Phase 2
Check-in study of immunotherapy plus another drug for lymphoma

This Phase 2 trial tests whether combining sintilimab (an immunotherapy) with chidamide (an anticancer “epigenetic” drug) can shrink peripheral T-cell lymphoma that has come back or didn’t respond. It’s for adults who have measurable lymphoma spots and can safely take both medicines.

Shanghai, Shanghai Municipality
NCT06757387Not yet recruiting· Phase 1/Phase 2
Combination treatment for peripheral T-cell lymphoma that has returned

This trial tests a combination of two drugs, chidamide and golidocitinib, for peripheral T-cell lymphoma that has come back or not responded to earlier treatments. The goal is to see if this combination can help shrink or control the lymphoma.

NCT07072221Recruiting
Matching drugs trial for relapsed T-cell lymphoma

This trial tests a combination of three drugs (bendamustine, chidamide, and lenalidomide) for patients with peripheral T-cell lymphoma that has come back or not responded to treatment. It aims to see if this new combination can help when standard treatments have failed.

Suzhou, Jiangsu

Hear when a new Peripheral T Cell Lymphoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.