Keytruda with or without Sac-TMT for advanced squamous lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests the combination of pembrolizumab (Keytruda) with or without a new drug, sacituzumab tirumotecan (Sac-TMT), as initial treatment for advanced squamous non-small cell lung cancer. It aims to see if adding Sac-TMT after initial treatment helps keep cancer under control longer.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have stage IV (advanced) squamous non-small cell lung cancer.
- You should not have had prior chemotherapy or immunotherapy for lung cancer that has spread.
- You must be in generally good health (able to care for yourself) and have a life expectancy of at least 3 months.
- You must not have had previous treatment with TROP2-directed therapies or topoisomerase I inhibitors.
- You must not have active brain metastases, uncontrolled eye diseases, inflammatory bowel disease, or serious heart problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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