Iron infusion and heart-failure medicine for low-iron heart failure
Treatments studied
Part of Heart & circulation, Hormones & metabolism clinical trials.
This trial tests whether giving iron through a vein (IV) plus a common heart-failure medicine improves heart function and iron levels in people with heart failure and low iron. You may receive the combination or just the standard medicine, and the study will use MRI and blood tests to check your heart and iron.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- Your heart's pumping function is reduced (ejection fraction 40% or less).
- You have low iron levels (ferritin below 100, or ferritin 100–299 with low transferrin saturation).
- Your hemoglobin (the part of blood that carries oxygen) is between 9.5 and 13.5 mg/dL.
- You have not taken SGLT2 inhibitor medicines before (like empagliflozin or dapagliflozin).
- You do not have severe kidney disease (on dialysis or with very low kidney function).
- You do not have a pacemaker, ICD, or other implanted heart device.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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