Saline rinse for lung infection treatment
Part of Lungs & breathing clinical trials.
This study tests whether rinsing the infected space around the lung with salt water (saline) before giving enzyme medicine helps clear the infection better than just the enzyme medicine alone. It's for people with a serious lung infection (empyema) that requires a chest tube.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have signs of infection in the fluid around your lung (pus, low pH, low sugar, or bacteria).
- You are starting enzyme treatment (intrapleural lytic therapy) to break up the infected fluid.
- You do not have a bleeding disorder or low platelets, and you can stop blood thinners safely.
- You are not pregnant or nursing, or you are willing to have a pregnancy test.
- You do not have a tunneled pleural catheter in the same side of your chest now or recently.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether regularly flushing the chest tube with a small amount of liquid helps prevent blockages in people who have a severe lung infection that spreads to the chest cavity. If you need a chest tube for this type of infection, you may be able to join.
This trial compares using a special camera to look inside your chest (medical thoracoscopy) with standard care to treat infections in the fluid around the lungs. It aims to see if this procedure helps clear the infection better, possibly reducing the need for more invasive surgery or a longer hospital stay.
This study tests whether a lower dose of alteplase (a clot-busting medicine) given into the chest can improve healing of infected pleural fluid when drainage is incomplete. It may help reduce dosing-related side effects while still helping clear the infection-related fluid.
This study tests using a thin tube with a camera (thoracoscopy) to treat early-stage pleural infection, an infection in the space around the lungs. It may help drain the infection better and possibly reduce the need for more invasive surgery.
This trial tests two combinations of medicines for people with infected fluid around the lung that isn't draining well through a chest tube. The goal is to see which combination works better to clear the infection and improve recovery.
This trial tests if adding a simple saltwater rinse to standard chest tube drainage helps clear stubborn lung infections. It might be an option if you have an infected fluid pocket in your chest that isn't draining well.
Hear when a new Pleural Infection trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.