Clinical trials
Pleural Infection clinical trials
Below are recruiting pleural infection clinical trials, each written for real people, not researchers. We’re tracking 13 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07432373Recruiting
Comparing clot-busting drugs for lung infections
This trial tests two combinations of medicines for people with infected fluid around the lung that isn't draining well through a chest tube. The goal is to see which combination works better to clear the infection and improve recovery.
Cheras, Kuala LumpurAges 18 years+ - NCT06713382RecruitingPhase 2
Saline rinse for trapped lung infections
This trial tests if adding a simple saltwater rinse to standard chest tube drainage helps clear stubborn lung infections. It might be an option if you have an infected fluid pocket in your chest that isn't draining well.
Boston, MassachusettsAges 18 years+ - NCT07095361RecruitingPhase 4
Daily enzyme therapy for infected pleural fluid
This trial tests a once-daily enzyme treatment given through a chest tube to clear infected fluid from around the lungs. It may help people with complicated pneumonia or empyema who still have fluid buildup after initial drainage.
New Haven, ConnecticutAges 18 years+ - NCT07666464RecruitingPhase 3
Saline wash for complicated lung infections
This trial tests if washing the infected fluid in the chest with salt water (saline) early on helps treat complicated lung infections better than the usual care. It may improve recovery and reduce the need for surgery.
Amiens, PicardieAges 18 years+ - NCT07140003Enrolling by invitation
Comparing fluid and tissue cultures for pleural infection
This study compares how well cultures from the fluid around the lung work versus cultures from a tissue sample in people with infected pleural fluid. It may help doctors choose the best way to diagnose and treat the infection.
Alexandria, Chest DepartmentAges Any age - NCT06427538Recruiting
Chest drain flushing for lung infections
This study tests whether regularly flushing the chest tube with a small amount of liquid helps prevent blockages in people who have a severe lung infection that spreads to the chest cavity. If you need a chest tube for this type of infection, you may be able to join.
Sterling Heights, MichiganAges 18 years+ - NCT07625176Enrolling by invitation
App-guided decisions for lung lining disease
This trial tests whether a decision-support app helps doctors better manage conditions affecting the pleura (the lining around your lungs)—like collapsed lung, fluid buildup, or infection. You'd be randomly assigned to use the app approach or standard care, and the study tracks how well each works.
AalborgAges 18 years+ - NCT07337993Recruiting
Fungal chest infection: washing the chest cavity
This study tests a chest-washing procedure (lavage) for people with a fungal infection in the space between the lung and chest wall. It aims to see if this extra step helps clear the infection before or instead of surgery.
Lahore, Punjab ProvinceAges Any age - NCT05620329Recruiting
Pleural fluid registry for drainage in adults
This registry collects information from adults who have fluid around the lungs (pleural effusion) and need clinically indicated drainage because of infection or cancer. It helps researchers better understand these conditions and improve future care.
Chapel Hill, North CarolinaAges 18 years+ - NCT06434324Recruiting
Saline rinse for lung infection treatment
This study tests whether rinsing the infected space around the lung with salt water (saline) before giving enzyme medicine helps clear the infection better than just the enzyme medicine alone. It's for people with a serious lung infection (empyema) that requires a chest tube.
Rochester, MinnesotaAges 18 years+ - NCT05766124RecruitingPhase 2/Phase 3
Lower-dose clot-busting medicine for infected chest fluid
This study tests whether a lower dose of alteplase (a clot-busting medicine) given into the chest can improve healing of infected pleural fluid when drainage is incomplete. It may help reduce dosing-related side effects while still helping clear the infection-related fluid.
Hong Kong, Hong KongAges 18 years+ - NCT07211529Recruiting
Nerve block during chest surgery to reduce complications
This trial tests whether a numbing injection near the spine (paravertebral block) given during keyhole chest surgery can lower the risk of problems after surgery. It might help patients recover more comfortably.
Wuhan, HubeiAges 18–80 - NCT05797649Recruiting
Test a pleural fluid blood marker to tell heart failure vs others
This study checks whether a substance called NT-proBNP in pleural fluid can better identify if fluid around the lung is caused by heart failure. If you fit, the results may help doctors choose faster, more accurate diagnosis for your pleural effusion.
Hong Kong, New TerritoriesAges 18 years+
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Common questions
- Are there clinical trials for pleural infection?
- Yes. Clin2 currently lists 13 recruiting pleural infection studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pleural infection trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pleural infection trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.