Clin2
NCT06713382Possibly a fitRecruiting

Saline rinse for trapped lung infections

Pleural Effusion Associated With Pulmonary InfectionPleural Effusion DisorderPleural Effusions

Part of Lungs & breathing clinical trials.

This trial tests if adding a simple saltwater rinse to standard chest tube drainage helps clear stubborn lung infections. It might be an option if you have an infected fluid pocket in your chest that isn't draining well.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
96 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You have infected fluid around your lung, shown by lab tests or imaging.
  • Your chest tube has drained less than 200 mL in the last 24 hours.
  • Your doctor thinks you need extra medication to break up the infection.
  • An ultrasound or CT scan shows pockets of fluid (septations or loculations).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06727578Recruiting
Pleural irrigation with a new device

This trial tests a new device to wash out fluid that stays in the chest after a chest tube is placed. It might help people who cannot receive standard medication to break up this fluid within the first day after their chest tube is inserted.

Boston, Massachusetts
NCT06709456Recruiting
Draining fluid from lungs in the ICU

This trial tests whether draining fluid that builds up around the lungs helps patients with breathing problems in the intensive care unit. You may be eligible if you are in the ICU, have at least 2 cm of fluid on an ultrasound or CT scan, and need extra oxygen or a breathing machine.

Aalborg
NCT07592520Not yet recruiting· Phase 4
Testing Medication Injections for Lung Fluid Infections

This trial tests whether injecting two medications (tPA and DNase) through a chest tube helps treat serious lung infections with fluid buildup. The goal is to see if this approach reduces the need for surgery and helps patients recover faster.

Hanover, New Hampshire
NCT07419360Recruiting
Draining fluid from lungs in heart failure

This study tests whether draining fluid from around the lungs can help people with heart failure who are in the hospital. It looks at how this procedure affects breathing and recovery.

Albany, New York
NCT06434324Recruiting
Saline rinse for lung infection treatment

This study tests whether rinsing the infected space around the lung with salt water (saline) before giving enzyme medicine helps clear the infection better than just the enzyme medicine alone. It's for people with a serious lung infection (empyema) that requires a chest tube.

Rochester, Minnesota
NCT07666464Recruiting· Phase 3
Saline wash for complicated lung infections

This trial tests if washing the infected fluid in the chest with salt water (saline) early on helps treat complicated lung infections better than the usual care. It may improve recovery and reduce the need for surgery.

Amiens, Picardie

Hear when a new Pleural Effusion Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.