Saline rinse for trapped lung infections
Part of Lungs & breathing clinical trials.
This trial tests if adding a simple saltwater rinse to standard chest tube drainage helps clear stubborn lung infections. It might be an option if you have an infected fluid pocket in your chest that isn't draining well.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older.
- You have infected fluid around your lung, shown by lab tests or imaging.
- Your chest tube has drained less than 200 mL in the last 24 hours.
- Your doctor thinks you need extra medication to break up the infection.
- An ultrasound or CT scan shows pockets of fluid (septations or loculations).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new device to wash out fluid that stays in the chest after a chest tube is placed. It might help people who cannot receive standard medication to break up this fluid within the first day after their chest tube is inserted.
This trial tests whether draining fluid that builds up around the lungs helps patients with breathing problems in the intensive care unit. You may be eligible if you are in the ICU, have at least 2 cm of fluid on an ultrasound or CT scan, and need extra oxygen or a breathing machine.
This study tests a two-step treatment for infected fluid around the lungs called empyema. It uses two medicines (tPA and DNase) given through your chest tube to break up and clear the fluid, which may help your lung expand and avoid surgery.
This study tests whether rinsing the infected space around the lung with salt water (saline) before giving enzyme medicine helps clear the infection better than just the enzyme medicine alone. It's for people with a serious lung infection (empyema) that requires a chest tube.
This trial tests if washing the infected fluid in the chest with salt water (saline) early on helps treat complicated lung infections better than the usual care. It may improve recovery and reduce the need for surgery.
This study tests whether regularly flushing the chest tube with a small amount of liquid helps prevent blockages in people who have a severe lung infection that spreads to the chest cavity. If you need a chest tube for this type of infection, you may be able to join.
Hear when a new Pleural Effusion Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.