CAR-T therapy for adults with certain blood cancers
Part of Blood & lymphatic, Cancer, Immune system & allergy clinical trials.
This trial tests a type of immunotherapy called CAR-T cells that target two proteins (CD19 and CD22) on cancer cells. It may be an option for adults with B-cell acute lymphoblastic leukemia (ALL) or B-cell non-Hodgkin lymphoma (NHL) that has come back or not responded to earlier treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have B-cell ALL or B-cell NHL that has relapsed (come back) or is refractory (not responding) after at least one prior treatment.
- You are in reasonably good health for your age, with a life expectancy of at least 12 weeks.
- You have not received certain chemotherapy drugs (like bendamustine or fludarabine) or specific other treatments recently.
- You do not have a current serious infection, such as active hepatitis B or C, or uncontrolled other infections.
- You do not have severe heart problems, recent stroke, or other major organ issues that are not well controlled.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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