CAR-T therapy with or without stem cell transplant for B-cell leukemia
Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.
This trial tests a CD19-targeted CAR-T cell therapy (S1904) for people with B-cell acute lymphoblastic leukemia that has come back or not responded to treatment. After CAR-T, some patients may go on to a stem cell transplant. The goal is to see if the CAR-T can lead to remission and who needs a transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 12 and 65 years old.
- Your leukemia has come back after treatment or has not responded to at least 2 rounds of chemo.
- Your leukemia cells have the CD19 marker on them.
- You have not had a stem cell transplant before.
- You have not received CAR-T therapy before.
- Your organs (liver, kidneys, heart, lungs) are working well enough.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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