Clin2
NCT06447597Possibly a fitRecruiting

Study of B007 for Generalized Myasthenia Gravis

Generalized Myasthenia Gravis

Treatments studied

Part of Brain & nervous system, Cancer, Immune system & allergy clinical trials.

This trial tests a new drug called B007 for people with generalized myasthenia gravis who have specific antibodies and moderate to severe muscle weakness. It aims to see if the drug can improve daily activities and reduce symptoms.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
104 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • Diagnosed with generalized myasthenia gravis (not the mild eye-only type or very severe crisis)
  • Positive for AChR or MUSK antibodies in your blood
  • Moderate to severe symptoms: your MG-ADL score (a daily activity rating) is 5 or higher
  • On a stable dose of your usual myasthenia gravis treatments (like steroids or immunosuppressants)
  • Willing to use effective birth control during the study and for 1 year after the last drug dose (if applicable)

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07622342Not yet recruiting· Phase 2
Study of a new injection for myasthenia gravis

This trial tests an investigational drug called SHR-2173, given as an injection, for people with generalized myasthenia gravis. It aims to see if the drug can improve muscle strength and daily function.

Changsha, Hunan
NCT07294170Recruiting
Testing Multiple Treatments for Myasthenia Gravis

This trial tests multiple treatment combinations for people with myasthenia gravis (MG), a condition that causes muscle weakness. It aims to find safer and more effective options by comparing different therapies.

Carlsbad, California
NCT07556120Not yet recruiting· Phase 1
Study of HN2301 for generalized myasthenia gravis

This study tests a new medicine called HN2301 for people with generalized myasthenia gravis that has not improved with standard treatments. The goal is to see if it is safe and if it helps reduce symptoms.

Hefei, Anhui
NCT07039916Recruiting· Phase 3
Study of IMVT-1402 for mild to severe generalized myasthenia gravis

This trial tests an investigational drug called IMVT-1402 to see if it improves symptoms in people with generalized myasthenia gravis (gMG). If you have mild to severe gMG and are looking for new treatment options, this study may be a fit.

Huntsville, Alabama
NCT06193889Recruiting· Phase 2/Phase 3
Car-t cell therapy for generalized myasthenia gravis

This trial tests a new cell therapy (CAR-T cells) for people with generalized myasthenia gravis. It aims to reduce symptoms and improve daily life by targeting and destroying faulty immune cells.

Los Angeles, California
NCT07818291Not yet recruiting· Phase 1
Study of an injectable drug for generalized myasthenia gravis

This trial tests an experimental drug (EA5) injected under the skin or into a vein for people with a specific form of myasthenia gravis (caused by AChR antibodies). The goal is to find the safest dose and see how well it may reduce muscle weakness.

Beijing, Beijing Municipality

Hear when a new Generalized Myasthenia Gravis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.