Clin2
NCT06455319Possibly a fitRecruiting

Personalized ATG with or without verapamil for new type 1 diabetes

Type 1 Diabetes

Treatments studied

Part of Hormones & metabolism, Immune system & allergy clinical trials.

This trial tests a new way to give a medicine called anti-thymocyte globulin (ATG) with or without verapamil, a blood pressure drug. It aims to slow down the loss of insulin-making cells in people newly diagnosed with type 1 diabetes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
60 people
Ages
6 years to 35 years
Study type
Interventional

Who can take part

  • You must be between 6 and 35 years old.
  • You must have been diagnosed with type 1 diabetes in the last 100 days.
  • Your body must still make some insulin (a test called C-peptide measures this).
  • You must be willing to get a flu shot if it's flu season, and avoid live vaccines during the study.
  • You must not have a weak immune system, active infections, or certain medical conditions like heart disease or blood disorders.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07061574Recruiting· Phase 1/Phase 2
Immune treatment for new onset type 1 diabetes

This study tests a low dose of a drug that calms the immune system, followed by either another immune drug or a blood pressure medicine, to see if they can help preserve the body's ability to make insulin in people recently diagnosed with type 1 diabetes. It may help keep your own insulin production going longer.

San Francisco, California
NCT07199946Recruiting· Phase 1/Phase 2
Verapamil to protect insulin production in children with new type 1 diabetes

This study tests if verapamil (a common blood pressure medication) can help children newly diagnosed with type 1 diabetes keep making their own insulin for longer. It aims to preserve the body's own insulin-producing cells, which may reduce the amount of insulin injections needed.

Jönköping
NCT07493122Not yet recruiting· Phase 1
Study of a new immune therapy for type 1 diabetes

This trial tests an investigational drug that may help preserve the body's ability to make insulin in people with type 1 diabetes. It aims to slow the progression of the disease and reduce the need for insulin injections.

NCT05153070Recruiting· Phase 2
Cyclosporine then low-dose immune therapy for new type 1 diabetes

This Phase 2 study tests whether starting with cyclosporine and then giving low-dose IL-2 can better protect the body’s insulin-producing function after type 1 diabetes is diagnosed. It’s meant for people diagnosed very recently who have specific diabetes-related immune markers.

Paris
NCT07216391Recruiting· Phase 2
Trial to delay type 1 diabetes: teplizumab vs. ATG

This study compares two medicines (teplizumab and anti-thymocyte globulin) to see if they can delay the onset of type 1 diabetes in people who are at high risk but don't have symptoms yet. If you have certain diabetes-related antibodies in your blood, this trial might help keep full-blown diabetes away for longer.

Aurora, Colorado
NCT07670650Not yet recruiting· Phase 3
Study of a new treatment to preserve insulin-making cells in type 1 diabetes

This trial tests a medicine called anti-thymocyte globulin (h-ATG) to see if it can help people with type 1 diabetes keep making some of their own insulin. It may slow the loss of insulin-making cells and help manage blood sugar.

San Francisco, California

Hear when a new Type 1 diabetes trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.