Gastric bypass effects on common medicines
Part of Hormones & metabolism clinical trials.
This study looks at how gastric bypass surgery changes the way your body processes certain common medications for diabetes, blood pressure, and cholesterol. The goal is to help doctors prescribe the right doses after surgery so these medicines work as effectively as possible.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years of age or older.
- You need to be scheduled for gastric bypass surgery as part of your weight-loss treatment.
- You must have a condition linked to metabolic syndrome, such as type 2 diabetes, high blood pressure, or high cholesterol.
- For at least 2 weeks before the surgery, you must be taking one of these medications: amlodipine or candesartan (for blood pressure), rosuvastatin (for cholesterol), or metformin (for diabetes).
- You cannot have had a sleeve gastrectomy (a different type of weight-loss surgery) before.
- You must not have kidney or liver problems, and you must not be taking certain other medications that could interfere with the study drugs (like some antibiotics or antifungals).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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