Predicting lung infection outcomes using early bacteria tests
Part of Infections, Lungs & breathing clinical trials.
This trial tests a new way to predict how well patients with a ventilator-associated lung infection will respond to treatment. It uses two bronchoscopy samples to track bacteria levels and guide better care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have been on a breathing machine (ventilator) for more than 48 hours.
- You have at least two signs of a lung infection: fever (over 38.5°C), low body temperature (under 36.5°C), abnormal white blood cell count, or pus in your lung mucus.
- You are willing to have two bronchoscopies (a tube with a camera to collect lung samples) – one at the start and one after 3 days of treatment.
- The first bronchoscopy must show a single infection with a specific bacteria (Pseudomonas aeruginosa, Acinetobacter baumannii, Klebsiella pneumoniae, or Staphylococcus aureus) at a certain level.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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