Cognitive training with brain stimulation for memory problems
Part of Brain & nervous system, Mental health clinical trials.
This trial tests combining cognitive training (brain exercises) with a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) to improve thinking and memory in people with mild cognitive impairment related to small blood vessel disease (vascular dementia).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 50 and 85 years old.
- You have mild memory or thinking problems, with a score of 18 to 26 on a standard memory test (MMSE) and a very mild dementia rating (CDR 0.5).
- Your brain MRI confirms small spots in the deep parts of the brain (lacunes) or white matter changes, but not caused by a stroke, bleeding, or other conditions like multiple sclerosis.
- You do not have severe trouble speaking, physical disability, or a history of brain injury, epilepsy, encephalitis, or alcohol/drug addiction.
- You are not taking antipsychotic medications for more than five years, and you can safely have an MRI.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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