Gene-guided NAC to prevent TB drug liver injury
Treatments studied
Part of Infections clinical trials.
This trial tests whether a medicine called N-acetylcysteine (NAC) can help prevent liver damage caused by standard TB drugs. If you have a higher risk of liver injury based on your genes, you may be given NAC along with your TB treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have been newly diagnosed with tuberculosis (TB) and are starting standard TB treatment.
- You do not have HIV, any active liver disease, or abnormal liver test results.
- You are not pregnant or breastfeeding.
- You have no history of allergy to N-acetylcysteine (NAC).
- You do not have cancer or a serious condition like advanced kidney disease, heart failure, or severe lung disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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