Comparing targeted pills for EGFR-mutated lung cancer
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This study tests three different targeted pills (osimertinib, afatinib, dacomitinib) in people with advanced EGFR-mutated lung cancer who haven't had targeted therapy before. The goal is to find which pill works best and has the fewest side effects.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have non-small cell lung cancer (NSCLC) at stage III or IV, or that has come back and can't be cured.
- Your tumor has an EGFR mutation (a specific change in the cancer cells) that may respond to targeted pills.
- You have not had any targeted therapy (TKI) for your lung cancer before.
- You are 18 or older, and can be in any physical condition (WHO performance status).
- You agree to use effective birth control if you or your partner could become pregnant.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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