Combination therapy for advanced lung cancer with EGFR mutation
Treatments studied
Part of Cancer, Lungs & breathing clinical trials.
This trial tests combining a targeted pill (EGFR-TKI) with an antibody drug (bevacizumab) for people with advanced non-small cell lung cancer that has a specific EGFR mutation. The goal is to see if this combination works better than the pill alone as a first treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with non-small cell lung cancer that has an EGFR mutation (exon 19 deletion or L858R).
- You have not yet received any systemic treatment for your lung cancer (like chemotherapy or targeted pills).
- You are able to take care of yourself (ECOG score 0-2) and have a life expectancy of at least 3 months.
- You have at least one tumor outside the brain that can be measured.
- You have adequate organ function (blood counts, liver, kidney) and no serious heart problems or other cancers.
- You are not pregnant or breastfeeding, and you agree to use contraception if applicable.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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