Comparing two surgeries for fluid buildup in the brain
Part of Brain & nervous system clinical trials.
This study compares two surgical treatments for normal pressure hydrocephalus (fluid buildup in the brain). It tests whether a less invasive procedure (endoscopic third ventriculostomy) works as well as the standard shunt surgery to improve walking, memory, and bladder control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are over 40 years old
- Your symptoms (trouble walking, memory issues, or bladder control) started 3 to 24 months ago
- You have trouble walking, plus either memory or bladder problems (or both)
- You do not have another condition that fully explains your symptoms
- You have not had brain surgery before
- You are willing to have a lumbar puncture to test how you respond to fluid removal
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study uses a simple ultrasound test on the head to measure blood flow pulses in the brain. It aims to help doctors decide whether a patient with suspected normal pressure hydrocephalus should get a shunt, so the right people get the treatment.
This study looks at older adults with normal pressure hydrocephalus (a buildup of fluid in the brain) to see if certain tests, like a spinal tap, can predict who will benefit from a shunt (a tube that drains extra fluid). This could help patients and doctors decide together whether surgery is a good option.
This European study looks at people with early (prodromal) signs of idiopathic normal pressure hydrocephalus (iNPH), a condition that can affect walking and thinking. It uses brain imaging and brief walking/cognitive checks to see who has this early pattern and may benefit from further evaluation.
This study looks at how spinal fluid moves and flows in people with normal pressure hydrocephalus (NPH), a condition where extra fluid builds up in the brain and can cause problems with walking, thinking, or bladder control. Researchers hope to learn more about the condition, which could help improve diagnosis and treatment.
This study looks at brain scans and spinal fluid in people with normal pressure hydrocephalus (NPH) to understand how it affects thinking and walking. If you have NPH and are 60 or older, this research may help find better ways to diagnose and treat you.
This study uses a combination of tests (like brain scans, walking tests, and memory checks) to more accurately diagnose a brain fluid condition called 'normal pressure hydrocephalus' and to decide if surgery might help. The goal is to improve treatment choices for people with this condition.
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