Clin2
NCT06510465Possibly a fitNot yet recruiting

Weekly utidelone with cisplatin before surgery for breast cancer

Breast Cancer

Treatments studied

Part of Cancer, Skin clinical trials.

This trial tests a combination of two drugs, utidelone and cisplatin, given before surgery to shrink breast tumors. The goal is to make surgery more effective and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
143 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with invasive breast cancer that has not spread to distant organs.
  • Your tumor is larger than 2 cm, or has spread to nearby lymph nodes, or if smaller than 2 cm, it must be hormone receptor negative, HER2 positive, or have a high Ki-67 score.
  • You have at least one measurable tumor that can be assessed by imaging.
  • You are in good general health (ECOG score 0 or 1) and have adequate blood, liver, and kidney function.
  • You are not pregnant or breastfeeding, and if you could become pregnant, you agree to use effective birth control during the trial.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05420454Recruiting· Phase 4
Neoadjuvant treatment for breast cancer before surgery

This trial tests a treatment given before breast surgery to shrink breast cancer and improve outcomes based on your tumor type. Your eligibility depends on tumor size/stage, hormone and HER2 markers, and overall health checks.

Hangzhou, Zhejiang
NCT05983094Not yet recruiting· Phase 2
Utidelone before surgery for high-risk breast cancer

This trial tests a new chemotherapy drug called utidelone, given before surgery for early high-risk or locally advanced breast cancer. The goal is to see if this drug can shrink tumors and improve outcomes. It may be a treatment option for people who meet the specific criteria.

Beijing, Beijing Municipality
NCT07246317Not yet recruiting· Phase 2
Targeted therapy before surgery for HER2-positive breast cancer

This trial tests a combination of targeted drugs and chemotherapy before surgery for HER2-positive breast cancer. It aims to see if this approach can shrink or eliminate the tumor, making surgery more effective.

Guangzhou, Guangdong
NCT07021261Not yet recruiting· Phase 3
Adding utidelone to capecitabine after surgery for triple-negative breast cancer

This study tests whether adding utidelone (an investigational drug) to capecitabine (a standard chemo pill) after surgery can reduce the chance of breast cancer returning in patients with triple-negative breast cancer who still had cancer cells after neoadjuvant chemotherapy. Participation could help improve your treatment plan to lower the risk of recurrence.

NCT06162559Recruiting· Phase 1
Targeted therapy before surgery for HER2+ breast cancer

This trial tests a combination of three targeted drugs (trastuzumab, pertuzumab, and tucatinib) without chemotherapy before surgery for HER2-positive breast cancer. It aims to see if this approach can shrink tumors effectively while avoiding chemotherapy side effects.

Amsterdam
NCT06441890Recruiting· Phase 2
Personalized chemo before breast cancer surgery

This trial tests whether giving chemotherapy before surgery, guided by the genetic profile of your tumor, can improve outcomes for a specific type of HER2-positive breast cancer. It aims to tailor treatment to each person's cancer biology.

Chicago, Illinois

Hear when a new Breast cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.