PARP inhibitor or chemo plus immunotherapy after surgery for high-risk TNBC
Part of Cancer, Skin clinical trials.
This trial tests whether adding a PARP inhibitor or capecitabine (chemo) to a PD-1 inhibitor (immunotherapy) after surgery helps prevent triple-negative breast cancer from coming back. It's for people with high-risk disease who have completed initial treatment.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have been diagnosed with invasive breast cancer that is triple-negative (no estrogen, progesterone, or HER2 receptors).
- Your tumor stage must be T1c, N1-N2 or T2, N0-N2 or T3, N0-N2 or T4a-d, N0-N2 (your doctor will confirm this).
- Your general health must be good: normal blood counts, liver and kidney function, and heart function.
- You cannot have had chemotherapy or radiation for any other cancer before (except for certain very early-stage cancers).
- You must agree to use effective birth control if you could become pregnant, and you cannot be pregnant or breastfeeding.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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