Brain stimulation (iTBS) for depression and thinking changes
Part of Mental health clinical trials.
This study tests whether a type of brain stimulation called iTBS can improve depression and thinking skills. It uses a magnetic coil over the scalp and is done on multiple days.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have at least moderate depression (not mild).
- Your current depressive episode has lasted more than 2 weeks but less than 2 years.
- You have been on the same antidepressant medication for at least 3 weeks.
- You do not have bipolar disorder, borderline personality disorder, psychosis, or certain other mental health conditions.
- You have no history of seizures, neurological conditions, or metal implants in your body.
- You are not pregnant, and you are not taking antipsychotics or benzodiazepines.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a type of brain stimulation called TMS (transcranial magnetic stimulation) for people with depression that hasn't improved with at least two antidepressants. Researchers want to see if a faster version of TMS (theta-burst stimulation) helps reduce depression symptoms.
This study tests a type of brain stimulation (guided iTBS) to improve depression when standard antidepressant treatments haven’t helped. It also checks that the treatment is safe for people who can meet the study and scan safety requirements.
This study tests whether intermittent theta burst stimulation (a type of brain stimulation using a magnetic device) can help keep depression from coming back after it has improved. It focuses on people whose depression has responded to an earlier iTBS treatment and who are able to safely receive TMS.
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