Clin2
NCT06541444Possibly a fitRecruiting

NK520 cell therapy for returning or hard-to-treat AML

Relapsed/Refractory Acute Myeloid Leukemia

Part of Blood & lymphatic, Cancer clinical trials.

This trial tests a new cell therapy called NK520 for people whose acute myeloid leukemia (AML) has not responded to standard treatments or has returned after treatment. It aims to see if this treatment is safe and effective.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
9 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have acute myeloid leukemia (a type of blood cancer) that has come back after treatment or hasn't gotten better after at least 2 different treatments.
  • You are able to take care of yourself and do daily activities with little help.
  • Your major organs (like kidneys, liver, heart, lungs) are working well.
  • You do not have active infections like tuberculosis, HIV, syphilis, or uncontrolled hepatitis B or C.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06367673Recruiting· Phase 1
NK cell therapy for relapsed or refractory AML

This trial tests a new natural killer (NK) cell therapy for adults with acute myeloid leukemia (AML) that has returned or not responded to treatment. The therapy targets two specific markers (CLL1 or CD33) on leukemia cells. It aims to see if these immune cells can safely fight the cancer.

Hangzhou, Zhejiang
NCT04662788Not yet recruiting· Early Phase 1
NK cell and antibody treatment for relapsed AML

This early-phase study tests whether a treatment using NK cells plus monoclonal antibodies is safe and effective for adults with relapsed or hard-to-treat acute myeloid leukemia (AML). It’s mainly looking for safety, and whether the treatment can help control the leukemia.

Hangzhou, Zhejiang
NCT06027853Recruiting· Phase 1
NK cell therapy for relapsed or refractory AML patients

This trial tests a natural killer (NK) cell therapy that targets a protein called CLL1 on leukemia cells. It aims to help people whose acute myeloid leukemia (AML) has come back or not responded to other treatments.

Hangzhou, Zhejiang
NCT04658004Not yet recruiting· Early Phase 1
CAR-T therapy for AML that has relapsed or resisted treatment

This trial tests a lab-made immune cell treatment (CAR-T) made to target AML cells with a specific marker (NKG2D ligand). It’s for people whose acute myeloid leukemia (AML) has come back or didn’t respond to standard chemotherapy.

Hangzhou, Zhejiang
NCT06307054Recruiting· Phase 1
CLL-1 CAR-NK cells for relapsed or refractory AML

This trial tests a therapy made from your own immune cells, engineered to target a marker called CLL-1 on leukemia cells, for people whose AML has come back or hasn't responded to standard treatments.

Shanghai, Shanghai Municipality
NCT06783478Not yet recruiting· Phase 2
NK cell therapy to maintain AML remission

This trial tests whether a special immune cell infusion (NK cells) from a half-matched family donor can help keep your AML in remission after initial chemotherapy. It is meant for people who have recently achieved their first remission and are otherwise healthy enough for a second round of chemo.

Porto Alegre, Rio Grande do Sul

Hear when a new Relapsed/Refractory Acute Myeloid Leukemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.