Nkg2d car-t cells for relapsed or refractory aml
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a new type of cell therapy called NKG2D CAR-T for people with AML that has not responded to standard treatment or has come back. It aims to use your own immune cells, modified to attack the leukemia, to help you achieve remission.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed diagnosis of acute myeloid leukemia (AML) that has come back or not responded to treatment.
- Your leukemia cells must test positive for a specific marker called NKG2D ligand.
- Your bone marrow must show a certain amount of leukemia cells (more than 5% by microscope or 0.01% by a more sensitive test).
- Your liver, kidneys, and heart must be working well enough (based on blood tests and an echocardiogram).
- You must be reasonably active and able to care for yourself (ECOG score 0 to 2).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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