NK cell and antibody treatment for relapsed AML
Part of Blood & lymphatic, Cancer clinical trials.
This early-phase study tests whether a treatment using NK cells plus monoclonal antibodies is safe and effective for adults with relapsed or hard-to-treat acute myeloid leukemia (AML). It’s mainly looking for safety, and whether the treatment can help control the leukemia.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have AML confirmed on a biopsy or tissue test.
- Your AML is relapsed or not responding to standard chemo (for example, never achieved complete remission, remission lasted under 12 months, or you’ve had multiple relapses).
- Your bone marrow leukemia cell level is above the study’s cutoff (more than 5% by eye under a microscope and/or more than 0.01% by flow testing).
- Your liver, kidney, and bilirubin blood tests are within allowed ranges.
- Your heart and breathing are strong enough: heart pumping (LVEF) is at least 50%, oxygen level in room air is at least 92%, and there’s no active lung infection.
- You can have the key study safety checks: no severe brain bleeding/serious brain circulation problems, no uncontrolled severe infections, no pregnancy/breastfeeding, and you must be able to consent and have an expected survival of at least 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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