Bacteria study for IBD patients with ongoing abdominal pain
Part of Digestive system clinical trials.
This study looks at bacteria in your gut that may produce chemicals linked to ongoing pain in Crohn's disease or ulcerative colitis, even when the disease itself is not very active. Researchers want to understand why some people still have moderate to severe abdominal pain even after their inflammation has calmed down.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 70 years old
- You have Crohn's disease or ulcerative colitis
- You have had or currently have moderate to severe chronic abdominal pain that continues even when your colitis is in remission (with low inflammation on scans, fecal calprotectin under 200, or only mild inflammation seen on colonoscopy)
- You are not currently taking acid-reducing medications or antacids
- You have not taken antibiotics, antibacterial agents, or probiotics in the last 8 weeks
- You are not taking opioids or NSAIDs for pain (acetaminophen is okay)
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at why some people develop long-term pain after being newly diagnosed with ulcerative colitis or Crohn’s disease. It may help researchers understand the pain process and improve future treatments.
This study looks at how changes in gut bacteria (the microbiome) relate to inflammatory bowel disease, including ulcerative colitis and Crohn disease. It may help researchers understand what might improve symptoms or disease control.
This study looks at blood and/or tissue “molecular” (cell-level) reasons why treatments don’t fully work in adults with Crohn’s disease or ulcerative colitis. If you are starting a biologic or small-molecule medicine and still have moderate to severe symptoms, you may be able to contribute to research that helps improve future care.
This study collects samples to learn how gut microbes, genetics, and body chemistry may relate to Crohn’s disease or ulcerative colitis. Your information and samples may help researchers understand disease patterns, but it does not test a new drug.
This study follows adults with Crohn’s disease or ulcerative colitis when their treatment is changed. It collects health information and samples to better understand how treatment changes affect people over time.
This trial tests an online pain education program for people with Crohn's disease or ulcerative colitis who have chronic pain. It aims to help you manage pain without needing to visit a clinic.
Hear when a new Crohn’s disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.