Balloon vs. stent for split artery blockages
Part of Heart & circulation clinical trials.
This trial compares two ways to open a blocked artery that splits into two branches (a bifurcation): using a balloon coated with medicine (drug-coated balloon, or DCB) versus a drug-eluting stent (DES). The goal is to see which approach works better for patients with this type of blockage.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have chest pain (angina) or silent ischemia, or had a heart attack more than a week ago
- The blockage is in a blood vessel that splits into two branches (a bifurcation) and is not in the left main artery
- The blocked artery has not been treated before with a stent at the same spot
- You do not have a very weak heart (ejection fraction less than 30%) or a severe calcium buildup in the artery
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial compares two ways to open a specific type of heart blockage that involves both a main artery and a side branch. It tests whether using a drug-coated balloon (“hybrid strategy”) works as well as using a planned two-stent approach (“stepwise provisional strategy”).
This trial compares two ways to open blocked heart arteries: a drug-coated balloon (a small balloon that releases medicine) versus a drug-eluting stent (a tiny mesh tube that also releases medicine). It aims to find which option works better for people with relatively simple blockages.
This trial compares two treatments for new blockages in heart arteries: a drug-coated balloon (a tiny balloon that delivers medicine) versus a drug-eluting stent (a small mesh tube that releases medicine). The study hopes to see which approach keeps the artery open longer and is safer over time.
This study tests a drug-coated balloon (DCB) that releases two medicines (sirolimus and paclitaxel) to open blocked small heart arteries. It may help people with stable chest pain or recent, controlled heart events who have a narrowed small vessel.
This trial tests a new way to treat complex blockages in heart arteries where a side branch is also narrowed. It uses a drug-coated balloon to open the side branch, aiming to improve blood flow and reduce the need for repeat procedures.
This trial compares two treatments—stents and paclitaxel-coated balloons—for people with narrowed heart arteries that are small, long, or complex. It aims to find which option works better to restore blood flow.
Hear when a new Coronary artery disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.