Second TAVI for failing aortic valve replacement
Part of Heart & circulation clinical trials.
This trial is for people who have already had a TAVI (a minimally invasive aortic valve replacement) and now need a second procedure because the valve is failing. The study will test how well a redo TAVI works to fix the failing valve.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have had a transcatheter aortic valve replacement (TAVI) that is now not working properly.
- The valve problem is not just leakage around the valve (paravalvular leak).
- You do not have an active heart infection (endocarditis).
- You do not have a blood clot in the valve that hasn't been treated.
- You are expected to live at least 1 more year.
- You are an adult capable of giving consent and not pregnant or nursing.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study collects information from people who need a second heart valve placed inside a previously implanted one (called TAVI-in-TAVI). The goal is to learn more about how a specific valve (the Myval) works in this situation.
This study tests a new replacement valve for the aortic heart valve, delivered through a catheter (a thin tube) — a procedure called TAVR. It is for people who have severe aortic stenosis and are not good candidates for open-heart surgery.
This trial studies whether a new through-the-blood-vessel heart valve (TAVR) is safe and works well for people with severe aortic stenosis who are too risky for traditional surgery. If you qualify, you would be closely followed to check your symptoms and valve function over time.
This trial tests a second transcatheter aortic valve replacement (TAVR) procedure for patients whose first TAVR valve is failing. It focuses on structural problems inside the valve, not leakage around it.
This study follows people who successfully had their first TAVI but later needed their replacement valve treated again with a “redo” TAVI. It’s mainly about tracking outcomes and safety over time to better understand who may benefit from a repeat TAVI.
This trial compares two ways to treat a failing aortic valve that was replaced with a tissue valve during surgery: another surgical replacement or a less invasive catheter-based valve-in-valve procedure. It is for people with low to intermediate surgical risk who are between 18 and 75 years old.
Hear when a new Aortic Valve Stenosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.