Redo TAVR for failed transcatheter aortic valves
Part of Heart & circulation clinical trials.
This trial tests a second transcatheter aortic valve replacement (TAVR) procedure for patients whose first TAVR valve is failing. It focuses on structural problems inside the valve, not leakage around it.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a TAVR valve (made by Medtronic or Edwards) that is now failing because of a structural problem inside the valve.
- Your valve failure is not only due to leakage around the valve.
- You do not have active heart infection (endocarditis).
- You do not have a new blood clot in the valve that hasn't been treated.
- You are expected to live longer than 1 year.
- You are not in another study that could conflict with this one.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests whether TAVI (a procedure to replace your heart valve without open-heart surgery) can be done safely at centers that do not have on-site heart surgery backup. It looks at how well patients do after the procedure, focusing on safety and recovery.
This study tests whether continuing a beta-blocker (a heart medication) improves outcomes for people having a planned TAVR (a minimally invasive heart-valve replacement). It may help doctors decide whether to keep or stop this medicine after the procedure.
This study tests whether a less invasive valve replacement (TAVI) can be done safely in hospitals that don't have a full heart surgery team on site. If you have severe aortic stenosis and are 70 or older, this trial might offer a new option with a shorter recovery than open-heart surgery.
This study compares regular monitoring (“clinical surveillance”) versus replacing the aortic valve using a minimally invasive procedure called TAVR for people with moderate aortic stenosis. It aims to see which approach better reduces symptoms or heart damage over time.
This trial is for people who have already had a TAVI (a minimally invasive aortic valve replacement) and now need a second procedure because the valve is failing. The study will test how well a redo TAVI works to fix the failing valve.
This study follows people who successfully had their first TAVI but later needed their replacement valve treated again with a “redo” TAVI. It’s mainly about tracking outcomes and safety over time to better understand who may benefit from a repeat TAVI.
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