Clin2
NCT06558682Possibly a fitRecruiting

Pre-surgery treatment for HER2-positive cervical cancer

Uterine Cervical Neoplasms

Part of Cancer, Women’s health & pregnancy clinical trials.

This trial tests a treatment given before surgery for cervical cancer that is both squamous cell type and HER2-positive. It aims to see if this approach works better for patients with these specific markers.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
48 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must have a diagnosis of cervical squamous cell carcinoma (a common type of cervical cancer).
  • Your cancer must be HER2-positive (a protein that can help cancer grow).
  • You cannot have cervical adenocarcinoma (another type of cervical cancer).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05940896Recruiting· Phase 1
HER2-targeted drug with radiation for non-surgical solid cancers

This Phase 1 study tests a HER2-targeted antibody drug (RC48-ADC) given with radiation in people with locally advanced solid tumors that cannot be removed by surgery. It aims to find a safe way to use the treatment and see how well it works in cancers that have HER2 protein on their cells.

Jinan, Shandong
NCT06389006Recruiting· Phase 2
Combination therapy before surgery for HER2-low, hormone-positive breast cancer

This trial tests a combination of two drugs (disitamab vedotin and toripalimab) followed by chemotherapy before surgery for people with a specific type of breast cancer that is hormone receptor-positive and HER2-low. The goal is to see if this treatment can shrink the tumor and improve outcomes.

Shanghai, Fudan University Shanghai Cancer Center
NCT06178159Recruiting· Phase 2
New drug combo before surgery for HER2-positive breast cancer

This trial tests a new combination of drugs (DV plus pertuzumab, with or without toripalimab) given before surgery for HER2-positive breast cancer. The goal is to see if this treatment can shrink the tumor and improve outcomes.

Shanghai, Shanghai Municipality
NCT06966453Recruiting· Phase 1/Phase 2
Study of disitamab vedotin for HER2-positive advanced breast cancer

This study tests a new drug called disitamab vedotin for people with advanced breast cancer that has a certain amount of HER2 protein. Depending on your HER2 and hormone receptor status, you may be eligible for one of three groups, each with different prior treatment requirements.

Daphne, Alabama
NCT06155396Recruiting· Phase 2
Targeted drug combo for advanced cervical cancer

This trial tests a combination of two drugs: an antibody-drug conjugate (RC48-ADC) that targets HER2 on cancer cells, plus an immunotherapy (Zimberelimab) that helps your immune system attack the cancer. It is for people with advanced cervical cancer whose prior platinum-based chemotherapy has stopped working.

Bengbu, Anhui
NCT04879329Recruiting· Phase 2
Study for HER2-positive bladder cancer after limited treatment

This Phase 2 trial tests disitamab vedotin alone or with pembrolizumab for urothelial (bladder/urinary tract) cancer that has HER2-positive tumors. It aims to shrink tumors and improve outcomes, including for people who have had limited prior treatment or specific prior drug exposures.

Gilbert, Arizona

Hear when a new Uterine Cervical Neoplasms trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.