Extending window for clot-busting drug in medium vessel stroke
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This trial tests a clot-dissolving drug called tenecteplase given 4.5 to 24 hours after a stroke caused by a blockage in a medium-sized brain artery. It aims to see if waiting longer than usual still helps reduce disability.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You had a stroke with a blocked medium-sized artery in the brain (not a large one).
- You are 18 years or older.
- You were independent before the stroke (able to do daily activities without help).
- Your stroke symptoms are disabling, like trouble speaking, weakness, or vision loss.
- You can receive the drug between 4.5 and 24 hours after symptoms started or were last seen well.
- Your brain imaging shows the blocked area is not too damaged.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests whether a clot-dissolving drug called tenecteplase can improve recovery for people who had a large-vessel ischemic stroke 4.5 to 24 hours earlier and can’t have a mechanical clot removal procedure in time. If you join, you’ll get either tenecteplase or standard medical care, and the study will track your recovery and safety.
This trial tests a new clot-busting medicine called tenecteplase, given directly into the blood vessel in the brain, to treat strokes caused by a blockage in a medium-sized artery. The goal is to see if it can help restore blood flow and reduce disability, especially for patients who can be treated within 24 hours of stroke onset.
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