Clinical trials
Acute Ischemic Stroke clinical trials
Below are recruiting acute ischemic stroke clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07430917RecruitingPhase 2
Testing J147 for recent stroke from blocked artery
This trial tests a new drug, J147, for people who recently had a stroke caused by a blocked artery and have already had a procedure to reopen that artery. It aims to see if the drug can improve recovery.
Long Beach, CaliforniaAges 18–90 - NCT07231380Recruiting
Comparing two ways to remove clots in stroke
This study tests two methods of removing a large blood clot from a brain artery during stroke. The goal is to see which method helps restore blood flow faster and more safely.
Nashville, TennesseeAges 18 years+ - NCT06121336Recruiting
Tracking a blood marker to measure stroke recovery
This study is looking at a protein in the blood called brain-derived tau, which may increase after a stroke. By measuring it over time, doctors hope to learn more about how the brain is healing and possibly predict recovery.
Munich, BavariaAges 18 years+ - NCT05065216RecruitingPhase 2/Phase 3
Study drug for acute ischemic stroke started within 24 hours
This trial tests whether an investigational study drug can improve outcomes after an acute ischemic stroke (a stroke caused by blocked blood flow). You may be eligible if you are able to start treatment quickly after symptom onset and have a moderate stroke severity on a standard stroke exam.
Fairhope, AlabamaAges 18–90 - NCT07361302RecruitingPhase 3
Tenecteplase for stroke after 4.5 hours
This trial tests a clot-dissolving medicine called tenecteplase for people who had a stroke more than 4.5 hours ago. It may help you recover if given later than usual.
Buenos AiresAges 18 years+ - NCT05338697Recruiting
Early testing after stroke to predict recovery outcomes
This study checks early brain and arm/hand signals soon after a stroke to better predict how well people recover by about 90 days. It may help future, better-targeted stroke recovery studies by improving how recovery chances are measured early.
Birmingham, AlabamaAges 18 years+ - NCT07392450RecruitingPhase 2
Study of TAK-755 for adults with acute ischemic stroke
This trial tests if TAK-755 can help people who have had a moderate to severe stroke within the last 24 hours. It aims to see if the drug can improve recovery by protecting brain tissue that is still salvageable.
Scottsdale, ArizonaAges 18 years+ - NCT07764172Recruiting
Sarcopenia in acute ischemic stroke
This study looks at muscle loss (sarcopenia) in people who have had an acute ischemic stroke. It aims to understand how muscle wasting affects recovery, which may help improve care for stroke patients.
MoscowAges 50 years+ - NCT07371624RecruitingPhase 1/Phase 2
Study of B2065 for recent ischemic stroke
This trial tests an investigational drug called B2065 for people who have had a recent ischemic stroke (a stroke caused by a blockage in a blood vessel in the brain). The goal is to see if it is safe and if it might help improve recovery when given within 36 hours of stroke symptoms starting.
BeijingAges 18–75 - NCT07163299Enrolling by invitationPhase 1/Phase 2
Cooling artery treatment with magnesium for stroke clot removal
This trial tests adding a cooled magnesium solution directly into the brain artery during standard clot removal to see if it helps limit brain damage and improve recovery. The magnesium and cooling aim to protect brain tissue while the clot is being taken out.
Xuzhou, JiangsuAges 18–80 - NCT07491952Recruiting
Continuous Dual Aspiration for Stroke With Zoom System
This trial tests a new way to remove blood clots from the brain using the Zoom System with a continuous double-suction technique (CDAT). It aims to see how well this approach works for people having a stroke caused by a large vessel blockage.
Huntsville, AlabamaAges 18 years+ - NCT07749170Recruiting
Stroke treatment for blockages in smaller brain arteries
This study looks at how well a special catheter system works to remove blood clots from smaller arteries in the brain after a stroke. It aims to see if this treatment helps people recover better.
Knoxville, TennesseeAges 18 years+ - NCT06315231RecruitingPhase 2
Stroke Recovery Thinking Trial for Recent Stroke Patients
This study tests an under-the-tongue tablet (edaravone dexborneol) to help thinking and memory problems that can happen after an ischemic stroke. It may help people who recently had a stroke and now have trouble with attention, memory, or planning.
Fuyang, AnhuiAges 40–80 - NCT07369999RecruitingPhase 3
Butylphthalide plus tenecteplase for mild disabling stroke
This trial tests whether adding butylphthalide (a drug that improves blood flow) to the standard clot-busting medicine tenecteplase can help people with mild but disabling strokes recover better. If you have had a mild stroke within the last 4.5 hours and are 18–80, this study might be an option for you.
Changsha, HunanAges 18–80 - NCT07001267Recruiting
Comparing two anesthetics for stroke procedure recovery
This trial tests whether a sedative given through an IV or a gas you breathe affects recovery after surgery to remove a blood clot in the brain. It may help find the best way to keep you comfortable during the procedure to improve how well you do after three months.
Kansas City, KansasAges 18 years+ - NCT06843356Recruiting
Endovascular treatment for worsening mild stroke with basilar artery blockage
This trial tests a procedure to open a blocked artery in the back of the brain (basilar artery) for people who had a mild stroke that later got worse. If you are eligible, you may receive this treatment up to 24 hours after your symptoms worsen.
Wuhu, AnhuiAges 18 years+ - NCT07294209RecruitingPhase 4
Low-dose tenecteplase for older adults with stroke
This trial tests a lower dose of the clot-busting drug tenecteplase in people aged 70 and older who have had an ischemic stroke. It aims to see if this treatment is safe and effective for older patients when given within 4.5 hours of symptoms starting.
Chongqing, Chongqing MunicipalityAges 70 years+ - NCT07003386RecruitingPhase 2/Phase 3
Galantamine for recent ischemic stroke
This trial tests a plant-based medicine called galantamine, given within 3 days of an ischemic stroke, to see if it helps recovery. It combines Western and Traditional Chinese Medicine approaches and aims to understand how the treatment works.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT07747701Recruiting
Monitoring brain blood flow after stroke treatment to predict recovery
This study looks at whether monitoring brain blood flow after a blocked artery is opened can help predict if the treatment will be successful. It may help doctors identify who might need additional help after stroke treatment.
BeijingAges 18 years+ - NCT07599904Recruiting
Real-world study of Medtronic stroke treatment devices
This registry tracks how Medtronic's FDA-approved devices work in treating acute ischemic stroke (a type of stroke caused by a blood clot) in everyday clinical practice. Researchers collect information to understand device safety and effectiveness outside of formal clinical trials.
Flint, MichiganAges 18 years+ - NCT07107022Recruiting
Study of Penumbra System for acute ischemic stroke
This study is collecting information on how well the Penumbra System works and how safe it is when used to remove blood clots in people having a certain type of stroke. It is for patients who are eligible for mechanical thrombectomy (a procedure to remove the clot) using this device as the first treatment.
Nedlands, Western AustraliaAges 18–80 - NCT07324837RecruitingPhase 3
Study of a clot-busting drug for stroke up to 24 hours later
This trial tests a single dose of a new clot-dissolving medicine for people who had a stroke 4.5 to 24 hours ago. It may help if you cannot have standard treatments like a clot-removal procedure or other clot-busting drugs.
Ryazan, Ryazan OblastAges 18 years+ - NCT07085390Recruiting
Comparing two catheters for stroke clot removal
This study compares two types of catheters (thin tubes) used during a stroke procedure to remove a blood clot. The goal is to see which one works better for clearing blockages in large blood vessels in the brain.
Tampa, FloridaAges 18 years+ - NCT07405762Recruiting
Stroke recovery after blood clot removal: brain blood flow study
This trial looks at how blood flow and brain activity change in the first days after a stroke caused by a large blockage in the front part of the brain. It tests if certain patterns can help predict recovery after a procedure to remove the clot.
Xi'an, Shan'xiAges 18–85
Hear when a new Acute Ischemic Stroke trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Acute Ischemic Stroke trials by city
Studies with a site in or near these metro areas.
Acute Ischemic Stroke trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for acute ischemic stroke?
- Yes. Clin2 currently lists 459 recruiting acute ischemic stroke studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a acute ischemic stroke trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a acute ischemic stroke trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.