Clin2
NCT06559644Possibly a fitNot yet recruiting

Hema-NeoTIL01 cell therapy for relapsed or refractory acute leukemia

Leukemia, Myeloid, AcuteB-cell Acute Lymphoblastic Leukemia

Part of Blood & lymphatic, Cancer, Immune system & allergy, Infections clinical trials.

This trial tests a new cell therapy called Hema-NeoTIL01 for people whose B-ALL or AML leukemia has come back or stopped responding to treatment. It aims to find out if these special immune cells can help control the leukemia.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
20 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You are 18 to 69 years old.
  • You have B-cell acute lymphoblastic leukemia (B-ALL) or acute myeloid leukemia (AML) that has returned or is not responding to standard treatments.
  • You have tried chemotherapy but it did not work, or the leukemia came back after treatment.
  • If you had CAR-T cell therapy before and it did not work or the leukemia came back, you may still join.
  • Your heart, liver, kidneys, and lungs are working well enough based on tests.
  • You are not pregnant and agree to use birth control for one year after treatment.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06056752Recruiting· Phase 1
CAR-T cell therapy for B-cell acute lymphoblastic leukemia

This trial tests a new cell therapy (QH103) for people with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to treatment. The therapy uses specially modified immune cells to find and kill cancer cells that have a protein called CD19 on their surface.

Hefei, Anhui
NCT04227015Recruiting· Early Phase 1
Study of a CD19 CAR T-cell treatment for relapsed leukemia

This early-phase trial tests an injected “CAR T” cell therapy made to attack CD19-positive blood cancers that have come back or did not respond. If you qualify, the study checks whether the treatment can help control the cancer and is safe enough to study further.

Hangzhou, Zhejiang
NCT06641024Not yet recruiting· Phase 1
CAR-T cell therapy for relapsed or refractory B-ALL

This trial tests a new CAR-T cell treatment for adults with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or not responded to standard treatments. It aims to see if these immune cells can safely and effectively fight the cancer.

Shanghai
NCT03326921Recruiting· Phase 1
T cell treatment for leukemia after a bone marrow transplant

This early-phase trial tests an immune “T cell” therapy made to recognize a specific leukemia target. It is for people whose acute leukemia has come back (relapsed) or did not fully respond after receiving a donor stem cell transplant.

Seattle, Washington
NCT06347458Not yet recruiting· Phase 1
Cell therapy for children with returning or hard-to-treat AML

This trial tests a new cell therapy (BG1805) for children whose acute myeloid leukemia (AML) has returned or not responded to standard treatment. The therapy targets a specific marker on leukemia cells called CLL-1 and aims to help the immune system fight the cancer.

NCT06499025Enrolling by invitation· Early Phase 1
T-cell therapy for a type of AML with the AML1-ETO gene

This trial tests a personalized cell therapy that uses your own immune cells (T cells) to target a specific protein (AML1-ETO) found in certain AML cells. It is for patients whose leukemia has come back or not gone away after standard treatment.

Shenzhen, Guangdong

Hear when a new Leukemia, Myeloid, Acute trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.