Study of a new drug for heart failure with preserved pumping ability
Part of Heart & circulation clinical trials.
This trial tests an investigational drug for people with a type of heart failure where the heart pumps normally but is stiff. The goal is to see if the drug can improve symptoms and quality of life.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with heart failure for at least 6 months and are in a stable condition (NYHA Class II or III).
- Your heart's pumping strength (ejection fraction) is 50% or higher.
- You have had previous tests showing signs of heart failure.
- Your bone marrow and major organs (like kidneys and liver) are working well enough.
- You have been on stable heart failure medications for at least 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial studies people who have heart failure symptoms but whose heart pumping strength is largely preserved. It aims to better understand this specific type of heart failure and how best to treat or evaluate it.
This study tests an investigational medication called elecoglipron to see if it can improve heart and blood vessel outcomes in people with heart failure with preserved or mildly reduced ejection fraction. If you join, you will receive either the study drug or a placebo, and your heart health will be monitored over time.
This trial tests an investigational drug called VS-041 to see if it's safe and helps people with a type of heart failure where the heart pumps well but doesn't relax properly (HFpEF). It may be an option if you are 50 or older and have stable heart failure symptoms.
This study looks for people who may have heart failure with preserved pumping function, where the heart is stiff and doesn't fill properly. It aims to better understand and identify this condition to improve care.
This study looks at people with a type of heart failure where the heart pumps normally but still doesn't fill properly. Researchers are using ultrasound pictures of the heart (echocardiograms) and blood tests to better understand this condition and find better ways to treat it.
This trial uses a special heart MRI to create pressure-volume loops in people with heart failure who have a normal pumping strength (ejection fraction of 50% or higher). It aims to better understand heart function and could help guide future treatments. You may qualify if you have heart failure symptoms and specific heart structure or function changes.
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