Heart failure treatment study for people with preserved pumping function
Treatments studied
Part of Heart & circulation clinical trials.
This study tests an investigational medication called elecoglipron to see if it can improve heart and blood vessel outcomes in people with heart failure with preserved or mildly reduced ejection fraction. If you join, you will receive either the study drug or a placebo, and your heart health will be monitored over time.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have heart failure and are in New York Heart Association class II, III, or IV.
- Your ejection fraction (a measure of heart pumping strength) is greater than 40%.
- You have evidence of structural heart disease, like an enlarged heart or thickened heart muscle.
- Your body mass index (BMI) is 25 or higher.
- You do not have type 1 diabetes or poorly controlled diabetes (HbA1c below 10%).
- You have not had certain heart procedures or surgeries in the last 90 days, and you do not have other specific heart conditions.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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