Early medication for muscle spasms after spinal cord injury
Part of Bones, joints & muscles, Brain & nervous system, Injuries & trauma clinical trials.
This trial tests whether starting oral baclofen, a muscle relaxant, soon after a spinal cord injury reduces muscle spasms and improves recovery. It aims to help patients with acute spasticity, which are uncontrolled muscle tightness or jerks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have a spinal cord injury from a blunt event, not a penetrating injury like a gunshot or stab wound.
- Your injury is between the neck and the upper back (C0 to L1).
- You have some level of motor or sensory function preserved (AIS grades A to D).
- You can give informed consent and do not have severe brain or kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a surgery called selective dorsal rhizotomy that cuts some nerves to reduce muscle stiffness and spasms caused by a head or spine injury. It may be a safer and cheaper alternative to a baclofen pump, which delivers medicine to the spinal fluid. If you have spasticity from a traumatic injury, this procedure might help improve movement.
This trial tests a spinal cord stimulator to reduce muscle stiffness (spasticity) after a stroke. If you've had arm or leg tightness that hasn't improved with other treatments, this device might help you move more easily.
This trial tests if giving Botox injections early (within 20 weeks of injury) into the bladder muscle can help with bladder function and prevent problems. It may help people with recent, severe spinal cord injuries above the T6 level.
This study looks at how spinal cord injuries that happened before or during birth affect people. It may help researchers understand more about these injuries.
This trial tests whether a mild electrical stimulation applied to the skin over your spine can improve arm and hand function after a spinal cord injury or stroke. It is for people with some preserved movement in their upper body.
This trial tests if a treatment called ITB (intrathecal baclofen) can help reduce muscle stiffness in people with hereditary spastic paraplegia (HSP). Participants will receive the treatment and be followed over time to see how well it works.
Hear when a new Traumatic Spinal Cord Injury trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.